Reaching your goals in diabetes and obesity studies can be a challenge or a success depending on the reliability of your research models. The Leprdb mutation was discovered in 1966 in the inbred BKS mouse strain. This model has since been well characterized as a model of Type 2 diabetes mellitus, exhibiting commonly published metabolic symptoms including hyperglycemia and hyperinsulinemia.
From Dunn Nutritional Laboratory, Cambridge, United Kingdom; to Olac, United Kingdom, in 1979; to Harlan, United States in 2000. Harlan became Envigo in 2015, then Envigo was acquired by Inotiv in 2021.
Our breeding scheme maintains Dock7m and Leprdb in repulsion. These genes are closely linked; however, recombination could occur. Our mice are most likely nonrecombinants, but they have not been tested.
Description | Price | Currency |
---|---|---|
3-4 weeks | 159.55 | USD |
4-5 weeks | 159.55 | USD |
5-6 weeks | 163.05 | USD |
6-7 weeks | 167.20 | USD |
7-8 weeks | 171.05 | USD |
Over 8 weeks, add per week | 6.15 | USD |
Retired breeder/Surplus | 136.05 | USD |