ICR (CD-1^®) outbred mice

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Aging

Infantino R, Boccella S, Scuteri D, Perrone M, Ricciardi F, Vitale RM, Bonsale R, Parente A, Allocca I, Virtuoso A, De Luca C, Belardo C, Amodeo P, Gentile V, Cirillo G, Bagetta G, Luongo L, Maione S, Guida F., 2-pentadecyl-2-oxazoline prevents cognitive and social behaviour impairments in the Amyloid β-induced Alzheimer-like mice model: Bring the α2 adrenergic receptor back into play, Biomed Pharmacother. 2022 Dec;156:113844. doi: 10.1016/j.biopha.2022.113844. Epub 2022 Oct 15.

Hood, W. R. (2012)., A test of bone mobilization relative to reproductive demand: Skeletal quality is improved in cannibalistic females with large litters., Physiological and Biochemical Zoology : PBZ, 85(4), 385-396. doi:10.1086/666057 [doi]

Impellizzeri D, D'Amico R, Fusco R, Genovese T, Peritore AF, Gugliandolo E, Crupi R, Interdonato L, Di Paola D, Di Paola R, Cuzzocrea S, Siracusa R, Cordaro M., Açai Berry Mitigates Vascular Dementia-Induced Neuropathological Alterations Modulating Nrf-2/Beclin1 Pathways, Cells. 2022 Aug 22;11(16):2616. doi: 10.3390/cells11162616.

Margiani G, Castelli MP, Pintori N, Frau R, Ennas MG, Orrù V, Serra V, Fiorillo E, Fadda P, Marsicano G, De Luca MA., Adolescent self-administration of the synthetic cannabinoid receptor agonist JWH-018 induces neurobiological and behavioral alterations in adult male mice, Psychopharmacology (Berl). 2022 Oct;239(10):3083-3102. doi: 10.1007/s00213-022-06191-9. Epub 2022 Aug 9.

Smith, M. A., Michael, R., Aravindan, R. G., Dash, S., Shah, S. I., Galileo, D. S., & Martin-DeLeon, P. A. (2015)., Anatase titanium dioxide nanoparticles in mice: Evidence for induced structural and functional sperm defects after short-, but not long-, term exposure., Asian Journal of Andrology, 17(2), 261-268. doi:10.4103/1008-682X.143247 [doi]

Kujjo, L. L., Acton, B. M., Perkins, G. A., Ellisman, M. H., D'Estaing, S. G., Casper, R. F., . . . Perez, G. I. (2013)., Ceramide and its transport protein (CERT) contribute to deterioration of mitochondrial structure and function in aging oocytes, Mechanisms of Ageing and Development, 134(1-2), 43-52. doi:10.1016/j.mad.2012.12.001 [doi]

Portal-Nunez, S., Manassra, R., Lozano, D., Acitores, A., Mulero, F., Villanueva-Penacarrillo, M. L., . . . Esbrit, P. (2013)., Characterization of skeletal alterations in a model of prematurely aging mice, Age (Dordrecht, Netherlands), 35(2), 383-393. doi:10.1007/s11357-011-9372-8 [doi]

Torres-Guzman, A. M., Morado-Urbina, C. E., Alvarado-Vazquez, P. A., Acosta-Gonzalez, R. I., Chavez-Pina, A. E., Montiel-Ruiz, R. M., & Jimenez-Andrade, J. M. (2014)., Chronic oral or intraarticular administration of docosahexaenoic acid reduces nociception and knee edema and improves functional outcomes in a mouse model of complete freund's adjuvant-induced knee arthritis, Arthritis Research & Therapy, 16(2), R64. doi:10.1186/ar4502 [doi]

Salloum, F. N., Das, A., Samidurai, A., Hoke, N. N., Chau, V. Q., Ockaili, R. A., . . . Kukreja, R. C. (2012)., Cinaciguat, a novel activator of soluble guanylate cyclase, protects against ischemia/reperfusion injury: Role of hydrogen sulfide, American Journal of Physiology.Heart and Circulatory Physiology, 302(6), H1347-54. doi:10.1152/ajpheart.00544.2011 [doi]

Ben-Meir, A., Burstein, E., Borrego-Alvarez, A., Chong, J., Wong, E., Yavorska, T., . . . Jurisicova, A. (2015)., Coenzyme Q10 restores oocyte mitochondrial function and fertility during reproductive aging, Aging Cell, doi:10.1111/acel.12368 [doi]

Babayev E, Suebthawinkul C, Gokyer D, Parkes WS, Rivas F, Pavone ME, Hall AR, Pritchard MT, Duncan FE., Cumulus expansion is impaired with advanced reproductive age due to loss of matrix integrity and reduced hyaluronan., Aging Cell. 2023 Nov;22(11):e14004. doi: 10.1111/acel.14004. Epub 2023 Oct 18.

Schverer M, Donoso F, Mitchell A, Rea K, Fitzgerald P, Sen P, Roy BL, Stanton C, Dinan TG, Cryan JF, Schellekens H., Dietary Milk Phospholipids Attenuate Chronic Stress-Induced Changes in Behavior and Endocrine Responses across the Lifespan, Mol Nutr Food Res. 2022 Feb;66(3):e2100665. doi: 10.1002/mnfr.202100665. Epub 2021 Dec 16.

Cordaro M, D'Amico R, Fusco R, Peritore AF, Genovese T, Interdonato L, Franco G, Arangia A, Gugliandolo E, Crupi R, Siracusa R, Di Paola R, Cuzzocrea S, Impellizzeri D., Discovering the Effects of Fisetin on NF-κB/NLRP-3/NRF-2 Molecular Pathways in a Mouse Model of Vascular Dementia Induced by Repeated Bilateral Carotid Occlusion, Biomedicines. 2022 Jun 19;10(6):1448. doi: 10.3390/biomedicines10061448.

Mihajlovi? AI, Haverfield J, FitzHarris G., Distinct classes of lagging chromosome underpin age-related oocyte aneuploidy in mouse, Dev Cell. 2021 Aug 23;56(16):2273-2283.e3. doi: 10.1016/j.devcel.2021.07.022.

Morado-Urbina, C. E., Alvarado-Vazquez, P. A., Montiel-Ruiz, R. M., Acosta-Gonzalez, R. I., Castaneda-Corral, G., & Jimenez-Andrade, J. M. (2014)., Early, middle, or late administration of zoledronate alleviates spontaneous nociceptive behavior and restores functional outcomes in a mouse model of CFA-induced arthritis., Drug Development Research, 75(7), 438-448. doi:10.1002/ddr.21183 [doi]

Sigurdsson, S., & Gudbjarnason, S. (2013)., Effect of oral imperatorin on memory in mice, Biochemical and Biophysical Research Communications, 441(2), 318-320. doi:10.1016/j.bbrc.2013.10.036 [doi]

Wallace, I. J., Judex, S., & Demes, B. (2015)., Effects of load-bearing exercise on skeletal structure and mechanics differ between outbred populations of mice, Bone, 72, 1-8. doi:10.1016/j.bone.2014.11.013 [doi]

Van Tassell, B. W., Arena, R. A., Toldo, S., Mezzaroma, E., Azam, T., Seropian, I. M., . . . Abbate, A. (2012), Enhanced interleukin-1 activity contributes to exercise intolerance in patients with systolic heart failure, PloS One, 7(3), e33438. doi:10.1371/journal.pone.0033438 [doi]

Weixelbaumer, K. M., Drechsler, S., Wehrenpfennig, P., Khadem, A., Bahrami, S., Tichy, A., . . . Osuchowski, M. F. (2014), Estrus cycle status defined by vaginal cytology does not correspond to fluctuations of circulating estrogens in female mice, Shock (Augusta, Ga.), 41(2), 145-153. doi:10.1097/SHK.0000000000000070 [doi]

Daniels, C. R., Foster, C. R., Yakoob, S., Dalal, S., Joyner, W. L., Singh, M., & Singh, K. (2012)., Exogenous ubiquitin modulates chronic beta-adrenergic receptor-stimulated myocardial remodeling: Role in akt activity and matrix metalloproteinase expression, American Journal of Physiology.Heart and Circulatory Physiology, 303(12), H1459-68. doi:10.1152/ajpheart.00401.2012 [doi]

Liu, P., Huang, Z., & Gu, N. (2013)., Exposure to silver nanoparticles does not affect cognitive outcome or hippocampal neurogenesis in adult mice., Ecotoxicology and Environmental Safety, 87, 124-130. doi:10.1016/j.ecoenv.2012.10.014 [doi]

Shi, X., Wallis, A. M., Gerard, R. D., Voelker, K. A., Grange, R. W., DePinho, R. A., . . . Garry, D. J. (2012)., Foxk1 promotes cell proliferation and represses myogenic differentiation by regulating Foxo4 and Mef2., Journal of Cell Science, 125(Pt 22), 5329-5337. doi:10.1242/jcs.105239 [doi]

Wallace, I. J., Tommasini, S. M., Judex, S., Garland, T.,Jr, & Demes, B. (2012)., Genetic variations and physical activity as determinants of limb bone morphology: An experimental approach using a mouse model., American Journal of Physical Anthropology, 148(1), 24-35. doi:10.1002/ajpa.22028 [doi]

Hasky, N., Uri-Belapolsky, S., Goldberg, K., Miller, I., Grossman, H., Stemmer, S. M., . . . Shalgi, R. (2015)., Gonadotrophin-releasing hormone agonists for fertility preservation: Unraveling the enigma?, Human Reproduction (Oxford, England), 30(5), 1089-1101. doi:10.1093/humrep/dev037 [doi]

Xu, Y., Pan, J., Sun, J., Ding, L., Ruan, L., Reed, M., . . . O'Donnell, J. M. (2015)., Inhibition of phosphodiesterase 2 reverses impaired cognition and neuronal remodeling caused by chronic stress., Neurobiology of Aging, 36(2), 955-970. doi:10.1016/j.neurobiolaging.2014.08.028 [doi]

Ossato, A., Vigolo, A., Trapella, C., Seri, C., Rimondo, C., Serpelloni, G., & Marti, M. (2015). JWH-018 impairs sensorimotor functions in mice., JWH-018 impairs sensorimotor functions in mice., Neuroscience, 300, 174-188. doi:10.1016/j.neuroscience.2015.05.021 [doi]

Beauchamp, B., Ghosh, S., Dysart, M. W., Kanaan, G. N., Chu, A., Blais, A., . . . Harper, M. E. (2015)., Low birth weight is associated with adiposity, impaired skeletal muscle energetics and weight loss resistance in mic, International Journal of Obesity (2005), 39(4), 702-711. doi:10.1038/ijo.2014.120 [doi]

Hamisha, K. N., Tfilin, M., Yanai, J., & Turgeman, G. (2015)., Mesenchymal stem cells can prevent alterations in behavior and neurogenesis induced by Ass25-35 administration., Journal of Molecular Neuroscience : MN, 55(4), 1006-1013. doi:10.1007/s12031-014-0457-6 [doi]

Traina, G., Cataldi, S., Siccu, P., Loreti, E., Ferri, I., Sidoni, A., . . . Albi, E. (2017)., Mouse thyroid gland changes in aging: Implication of galectin-3 and sphingomyelinase., Mediators of Inflammation, 2017, 8102170. doi:10.1155/2017/8102170 [doi]

Dave A, Park EJ, Pezzuto JM., Multi-Organ Nutrigenomic Effects of Dietary Grapes in a Mouse Model., Antioxidants (Basel). 2023 Oct 1;12(10). pii: 1821. doi: 10.3390/antiox12101821.

Cordaro M, Modafferi S, D'Amico R, Fusco R, Genovese T, Peritore AF, Gugliandolo E, Crupi R, Interdonato L, Di Paola D, Impellizzeri D, Cuzzocrea S, Calabrese V, Di Paola R, Siracusa R., Natural Compounds Such as Hericium erinaceus and Coriolus versicolor Modulate Neuroinflammation, Oxidative Stress and Lipoxin A4 Expression in Rotenone-Induced Parkinson's Disease in Mice, Biomedicines. 2022 Oct 7;10(10):2505. doi: 10.3390/biomedicines10102505.

Gammie, S. C., Lee, G., Scotti, M. A., Stevenson, S. A., & Gessay, G. M. (2012)., Neurotensin induced egr-1 activity is altered in the postpartum period in mice, Brain Research, 1433, 47-55. doi:10.1016/j.brainres.2011.11.017 [doi]

Companys-Alemany J, Turcu AL, Schneider M, Müller CE, Vázquez S, Griñán-Ferré C, Pallàs M., NMDA receptor antagonists reduce amyloid-β deposition by modulating calpain-1 signaling and autophagy, rescuing cognitive impairment in 5XFAD mice, Cell Mol Life Sci. 2022 Jul 9;79(8):408. doi: 10.1007/s00018-022-04438-4.

Borgonetti V, Galeotti N., Novel Combination of Choline with Withania somnifera (L.) Dunal, and Bacopa monnieri (L.) Wetts Reduced Oxidative Stress in Microglia Cells, Promoting Neuroprotection., Int J Mol Sci. 2023 Sep 13;24(18). pii: 14038. doi: 10.3390/ijms241814038.

Nahab, F. B., Handforth, A., Brown, T., Shin, C., Quesada, A., Dong, C., . . . Hallett, M. (2012)., Octanoic acid suppresses harmaline-induced tremor in mouse model of essential tremor., Neurotherapeutics : The Journal of the American Society for Experimental NeuroTherapeutics, 9(3), 635-638. doi:10.1007/s13311-012-0121-1 [doi]

Ternianov, A., Perez-Ortiz, J. M., Solesio, M. E., Garcia-Gutierrez, M. S., Ortega-Alvaro, A., Navarrete, F., . . . Manzanares, J. (2012)., Overexpression of CB2 cannabinoid receptors results in neuroprotection against behavioral and neurochemical alterations induced by intracaudate administration of 6-hydroxydopamine., Neurobiology of Aging, 33(2), 421.e1-421.16. doi:10.1016/j.neurobiolaging.2010.09.012 [doi]

Cruz-Pereira JS, Moloney GM, Bastiaanssen TFS, Boscaini S, Tofani G, Borras-Bisa J, van de Wouw M, Fitzgerald P, Dinan TG, Clarke G, Cryan JF., Prebiotic supplementation modulates selective effects of stress on behavior and brain metabolome in aged mice, Neurobiol Stress. 2022 Nov 6;21:100501. doi: 10.1016/j.ynstr.2022.100501. eCollection 2022 Nov.

Melemedjian, O. K., Yassine, H. N., Shy, A., & Price, T. J. (2013)., Proteomic and functional annotation analysis of injured peripheral nerves reveals ApoE as a protein upregulated by injury that is modulated by metformin treatment., Molecular Pain, 9, 14-8069-9-14. doi:10.1186/1744-8069-9-14 [doi]

Dipali SS, King CD, Rose JP, Burdette JE, Campisi J, Schilling B, Duncan FE., Proteomic quantification of native and ECM-enriched mouse ovaries reveals an age-dependent fibro-inflammatory signature., Aging (Albany NY). 2023 Oct 27;15(20):10821-10855. doi: 10.18632/aging.205190. Epub 2023 Oct 27.

Drechsler, S., Weixelbaumer, K., Raeven, P., Jafarmadar, M., Khadem, A., van Griensven, M., . . . Osuchowski, M. F. (2012)., Relationship between age/gender-induced survival changes and the magnitude of inflammatory activation and organ dysfunction in post-traumatic sepsis., PloS One, 7(12), e51457. doi:10.1371/journal.pone.0051457 [doi]

Wiley JL, Barrus DG, Farquhar CE, Lefever TW, Gamage TF., Sex, species and age: Effects of rodent demographics on the pharmacology of ?(9)-tetrahydrocanabinol, Prog Neuropsychopharmacol Biol Psychiatry. 2021 Mar 2;106:110064. doi: 10.1016/j.pnpbp.2020.110064. Epub 2020 Aug 15.

Ben Yaakov T, Wasserman T, Aknin E, Savir Y., Single-cell analysis of the aged ovarian immune system reveals a shift towards adaptive immunity and attenuated cell function., Elife. 2023 Apr 25;12. pii: e74915. doi: 10.7554/eLife.74915.

Shalwala, M., Zhu, S. G., Das, A., Salloum, F. N., Xi, L., & Kukreja, R. C. (2014), Sirtuin 1 (SIRT1) activation mediates sildenafil induced delayed cardioprotection against ischemia-reperfusion injury in mice, PloS One, 9(1), e86977. doi:10.1371/journal.pone.0086977 [doi]

Ardizzone A, Bova V, Casili G, Filippone A, Campolo M, Lanza M, Esposito E, Paterniti I., SUN11602, a bFGF mimetic, modulated neuroinflammation, apoptosis and calcium-binding proteins in an in vivo model of MPTP-induced nigrostriatal degeneration, J Neuroinflammation. 2022 May 7;19(1):107. doi: 10.1186/s12974-022-02457-3.

Hartmann, U., Hulsmann, H., Seul, J., Roll, S., Midani, H., Breloy, I., . . . Paulsson, M. (2013)., Testican-3: A brain-specific proteoglycan member of the BM-40/SPARC/osteonectin family, Journal of Neurochemistry, 125(3), 399-409. doi:10.1111/jnc.12212 [doi]

Dabbah-Assadi F, Alon D, Golani I, Doron R, Kremer I, Beloosesky R, Shamir A., The influence of immune activation at early vs late gestation on fetal NRG1-ErbB4 expression and behavior in juvenile and adult mice offspring, Brain Behav Immun. 2019 Jul;79:207-215. doi: 10.1016/j.bbi.2019.02.002. Epub 2019 Feb 6.

Lanza M, Cucinotta L, Casili G, Filippone A, Basilotta R, Capra AP, Campolo M, Paterniti I, Cuzzocrea S, Esposito E., The Transcription Factor Nrf2 Mediates the Effects of Antrodia camphorata Extract on Neuropathological Changes in a Mouse Model of Parkinson's Disease., Int J Mol Sci. 2023 May 25;24(11). pii: 9250. doi: 10.3390/ijms24119250.

Miranda, A., Lopez-Cardona, A. P., Laguna-Barraza, R., Calle, A., Lopez-Vidriero, I., Pintado, B., & Gutierrez-Adan, A. (2014)., Transcriptome profiling of liver of non-genetic low birth weight and long term health consequences., BMC Genomics, 15, 327-2164-15-327. doi:10.1186/1471-2164-15-327 [doi]

Kim, J. Y., Ash, R. T., Ceballos-Diaz, C., Levites, Y., Golde, T. E., Smirnakis, S. M., & Jankowsky, J. L. (2013), Viral transduction of the neonatal brain delivers controllable genetic mosaicism for visualising and manipulating neuronal circuits in vivo, The European Journal of Neuroscience, 37(8), 1203-1220. doi:10.1111/ejn.12126 [doi]

Savriama Y, Romestaing C, Clair A, Averty L, Ulmann J, Ledevin R, Renaud S., Wild versus lab house mice: Effects of age, diet, and genetics on molar geometry and topography, J Anat. 2021 Aug 1. doi: 10.1111/joa.13529. Online ahead of print.

COVID-19

Huang WC, Zhou S, He X, Chiem K, Mabrouk MT, Nissly RH, Bird IM, Strauss M, Sambhara S, Ortega J, Wohlfert EA, Martinez-Sobrido L, Kuchipudi SV, Davidson BA, Lovell JF., SARS-CoV-2 RBD Neutralizing Antibody Induction is Enhanced by Particulate Vaccination, Adv Mater. 2020 Oct 28:e2005637. doi: 10.1002/adma.202005637. Online ahead of print.

General studies

Guidi A, Prasanth Saraswati A, Relitti N, Gimmelli R, Saccoccia F, Sirignano C, Taglialatela-Scafati O, Campiani G, Ruberti G, Gemma S., (+)-(R)- and (-)-(S)-Perhexiline maleate: Enantioselective synthesis and functional studies on Schistosoma mansoni larval and adult stages, Bioorg Chem. 2020 Sep;102:104067. doi: 10.1016/j.bioorg.2020.104067. Epub 2020 Jun 30.

Codony S, Pujol E, Pizarro J, Feixas F, Valverde E, Loza MI, Brea JM, Saez E, Oyarzabal J, Pineda-Lucena A, PĂŠrez B, PĂŠrez C, RodrĂguez-Franco MI, Leiva R, Osuna S, Morisseau C, Hammock BD, VĂĄzquez-Carrera M, VĂĄzquez S., 2-Oxaadamant-1-yl Ureas as Soluble Epoxide Hydrolase Inhibitors: In Vivo Evaluation in a Murine Model of Acute Pancreatitis, J Med Chem. 2020 Sep 10;63(17):9237-9257. doi: 10.1021/acs.jmedchem.0c00310. Epub 2020 Aug 25.

Khazma T, Golan-Vaishenker Y, Guez-Haddad J, Grossman A, Sain R, Weitman M, Plotnikov A, Zalk R, Hons M, Opatowsky Y., A duplex structure of SARM1 octamers stabilized by a new inhibitor, Cell Mol Life Sci. 2022 Dec 23;80(1):16. doi: 10.1007/s00018-022-04641-3.

Khazma T, Golan-Vaishenker Y, Guez-Haddad J, Grossman A, Sain R, Weitman M, Plotnikov A, Zalk R, Yaron A, Hons M, Opatowsky Y., A duplex structure of SARM1 octamers stabilized by a new inhibitor., Cell Mol Life Sci. 2022 Dec 23;80(1):16. doi: 10.1007/s00018-022-04641-3. Erratum in: Cell Mol Life Sci. 2023 Feb 23;80(3):68.

Mundaca-Uribe R, Holay M, Abbas A, Askarinam N, Sage-Sepulveda JS, Kubiatowicz L, Fang RH, Zhang L, Wang J., A Microstirring Oral Pill for Improving the Glucose-Lowering Effect of Metformin., ACS Nano. 2023 May 23;17(10):9272-9279. doi: 10.1021/acsnano.3c00581. Epub 2023 May 12.

Colaneri, A., Wang, T., Pagadala, V., Kittur, J., Staffa, N. G.,Jr, Peddada, S. D., . . . Birnbaumer, L. (2013), A minimal set of tissue-specific hypomethylated CpGs constitute epigenetic signatures of developmental programming., PloS One, 8(9), e72670. doi:10.1371/journal.pone.0072670 [doi]

Couch, Y., Xie, Q., Lundberg, L., Sharp, T., & Anthony, D. C. (2015), A model of post-infection fatigue is associated with increased TNF and 5-HT2A receptor expression in mice, PloS One, 10(7), e0130643. doi:10.1371/journal.pone.0130643 [doi]

DebRoy, S., Saldana, M., Travisany, D., Montano, A., Galloway-Pena, J., Horstmann, N., . . . Shelburne, S. A. (2016), A multi-serotype approach clarifies the catabolite control protein A regulon in the major human pathogen group A streptococcus., Scientific Reports, 6, 32442. doi:10.1038/srep32442 [doi]

Kesserwan S, Mao L, Sharafieh R, Kreutzer DL, Klueh U., A pharmacological approach assessing the role of mast cells in insulin infusion site inflammation, Drug Deliv Transl Res. 2021 Sep 24. doi: 10.1007/s13346-021-01070-w. Online ahead of print.

Corbin KL, West HL, Brodsky S, Whitticar NB, Koch WJ, Nunemaker CS., A Practical Guide to Rodent Islet Isolation and Assessment Revisited, Biol Proced Online. 2021 Mar 1;23(1):7. doi: 10.1186/s12575-021-00143-x.

Mwirigi J, Kume M, Hassler SN, Ahmad A, Ray PR, Jiang C, Chamessian A, Mseeh N, Ludwig BP, Rivera BD, Nieman MT, Van de Ven T, Ji RR, Dussor G, Boitano S, Vagner J, Price TJ., A Role for Protease Activated Receptor Type 3 (PAR3) in Nociception Demonstrated Through Development of a Novel Peptide Agonist, J Pain. 2021 Jun;22(6):692-706. doi: 10.1016/j.jpain.2020.12.006. Epub 2021 Jan 9.

Eid Mutlak Y, Aweida D, Volodin A, Ayalon B, Dahan N, Parnis A, Cohen S., A signaling hub of insulin receptor, dystrophin glycoprotein complex and plakoglobin regulates muscle size, Nat Commun. 2020 Mar 13;11(1):1381. doi: 10.1038/s41467-020-14895-9.

Lebar T, Lainšček, D, Merljak E, Aupič J, Jerala R., A tunable orthogonal coiled-coil interaction toolbox for engineering mammalian cells, Nat Chem Biol. 2020 May;16(5):513-519. doi: 10.1038/s41589-019-0443-y. Epub 2020 Jan 6.

Caballero-Camino FJ, Rodrigues PM, WÃ¥ngsell F, Agirre-Lizaso A, Olaizola P, Izquierdo-Sanchez L, Perugorria MJ, Bujanda L, Angelin B, Straniero S, WallebÃ¤ck A, Starke I, Gillberg PG, StrÃ¤ngberg E, Bonn B, Mattsson JP, Madsen MR, Hansen HH, LindstrÃ¶m E, Ã…kerblad P, Banales JM., A3907, a systemic ASBT inhibitor, improves cholestasis in mice by multiorgan activity and shows translational relevance to humans., Hepatology. 2023 Sep 1;78(3):709-726. doi: 10.1097/HEP.0000000000000376. Epub 2023 Apr 1.

Gore R, Esmail T, Pflepsen K, Marron Fernandez de Velasco E, Kitto KF, Riedl MS, Karlen A, McIvor RS, Honda CN, Fairbanks CA, Vulchanova L., AAV-mediated gene transfer to colon-innervating primary afferent neurons., Front Pain Res (Lausanne). 2023 Aug 4;4:1225246. doi: 10.3389/fpain.2023.1225246. eCollection 2023.

Interdonato L, Marino Y, Franco GA, Arangia A, D'Amico R, Siracusa R, Cordaro M, Impellizzeri D, Fusco R, Cuzzocrea S, Paola RD., Açai Berry Administration Promotes Wound Healing through Wnt/β-Catenin Pathway, Int J Mol Sci. 2023 Jan 3;24(1):834. doi: 10.3390/ijms24010834.

Interdonato L, Marino Y, Franco GA, Arangia A, D'Amico R, Siracusa R, Cordaro M, Impellizzeri D, Fusco R, Cuzzocrea S, Paola RD., Acai Berry Administration Promotes Wound Healing through Wnt/β-Catenin Pathway., Int J Mol Sci. 2023 Jan 3;24(1). pii: 834. doi: 10.3390/ijms24010834.

Siracusa R, D'Amico R, Fusco R, Impellizzeri D, Peritore AF, Gugliandolo E, Crupi R, Interdonato L, Cordaro M, Cuzzocrea S, Di Paola R., Açai Berry Attenuates Cyclophosphamide-Induced Damage in Genitourinary Axis-Modulating Nrf-2/HO-1 Pathways, Antioxidants (Basel). 2022 Nov 28;11(12):2355. doi: 10.3390/antiox11122355.

Cai H , Ao Z , Hu L , Moon Y , Wu Z , Lu HC , Kim J , Guo F ., Acoustofluidic assembly of 3D neurospheroids to model Alzheimer's disease, Analyst. 2020 Sep 28;145(19):6243-6253. doi: 10.1039/d0an01373k.

Simăo-Gurge RM, Thakre N, Strickland J, Isoe J, Delacruz LR, Torrevillas BK, Rodriguez AM, Riehle MA, Luckhart S., Activation of Anopheles stephensi Pantothenate Kinase and Coenzyme A Biosynthesis Reduces Infection with Diverse Plasmodium Species in the Mosquito Host, Biomolecules. 2021 May 29;11(6):807. doi: 10.3390/biom11060807.

Lagunas-Herrera, HipĂłlita; Tortoriello, Jaime; Herrera-Ruiz, Maribel; MartĂnez-HenĂĄndez, Gabriela Belen; Zamilpa, Alejandro; SantamarĂa, LucĂa Aguilar; Lorenzana, Mario GarcĂa; Lombardo-Earl, Galia; JimĂŠnez-Ferrer, Enrique;, Acute and Chronic Antihypertensive Effect of Fractions, Tiliroside and Scopoletin from Malva parviflora., Biological & pharmaceutical bulletin Vol.42, 2019

Lagunas-Herrera, Hipólita; Tortoriello, Jaime; Herrera-Ruiz, Maribel; Martínez-Henández, Gabriela Belen; Zamilpa, Alejandro; Santamaría, Lucía Aguilar; Lorenzana, Mario García; Lombardo-Earl, Galia; Jiménez-Ferrer, Enrique;, Acute and Chronic Antihypertensive Effect of Fractions, Tiliroside and Scopoletin from Malva parviflora., Biological & pharmaceutical bulletin Vol.42, 2019

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Nguyen HM, Kowacich DJ, Wasserberg G., Temporal Bet-Hedging in Sand Fly Oviposition: Pharate Phlebotomus papatasi Sand Fly Neonates Regulate Hatching Time in Response to Organic Matter and Proximity to Conspecific Eggs, Vector Borne Zoonotic Dis. 2021 Apr;21(4):275-279. doi: 10.1089/vbz.2020.2689. Epub 2020 Dec 14.

Toma, Wisam; Kyte, S Lauren; Bagdas, Deniz; Jackson, Asti; Meade, Julie A; Rahman, Faria; Chen, Zhi-Jian; Del Fabbro, Egidio; Cantwell, Lucas; Kulkarni, Abhijit; Thakur, Ganesh A; Papke, Roger L; Bigbee, John W; Gewirtz, David A; Damaj, M Imad, The ?7 nicotinic receptor silent agonist R-47 prevents and reverses paclitaxel-induced peripheral neuropathy in mice without tolerance or altering nicotine reward and withdrawal., Experimental neurology Vol.320, 2019

Vanneste M, Venzke A, Guin S, Fuller AJ, Jezewski AJ, Beattie SR, Krysan DJ, Meyers MJ, Henry MD., The anti-cancer efficacy of a novel phenothiazine derivative is independent of dopamine and serotonin receptor inhibition., Front Oncol. 2023 Oct 16;13:1295185. doi: 10.3389/fonc.2023.1295185. eCollection 2023.

Arias HR, Tae HS, Micheli L, Yousuf A, Manetti D, Romanelli MN, Ghelardini C, Adams DJ, Di Cesare Mannelli L., The Antinociceptive Activity of (E)-3-(thiophen-2-yl)- N -(p-tolyl)acrylamide in Mice Is Reduced by (E)-3-(furan-2-yl)- N -methyl- N -(p-tolyl)acrylamide Through Opposing Modulatory Mechanisms at the α7 Nicotinic Acetylcholine Receptor., Anesth Analg. 2023 Sep 1;137(3):691-701. doi: 10.1213/ANE.0000000000006461. Epub 2023 Apr 14.

Bayer J, Vaghela R, Drechsler S, Osuchowski MF, Erben RG, Andrukhova O., The bone is the major source of high circulating intact fibroblast growth factor-23 in acute murine polymicrobial sepsis induced by cecum ligation puncture, PLoS One. 2021 May 14;16(5):e0251317. doi: 10.1371/journal.pone.0251317. eCollection 2021.

Glazier VE, Kramara J, Ollinger T, Solis NV, Zarnowski R, Wakade RS, Kim M-J, Weigel GJ, Liang S-H, Bennett RJ, Wellington M, Andes DR, Stamnes MA, Filler SG, Krysan DJ., The Candida albicans reference strain SC5314 contains a rare, dominant allele of the transcription factor Rob1 that modulates filamentation, biofilm formation, and oral commensalism., mBio. 2023 Oct 31;14(5):e0152123. doi: 10.1128/mbio.01521-23. Epub 2023 Sep 22.

Kondev V, Morgan A, Najeed M, Winters ND, Kingsley PJ, Marnett L, Patel S., The Endocannabinoid 2-Arachidonoylglycerol Bidirectionally Modulates Acute and Protracted Effects of Predator Odor Exposure, Biol Psychiatry. 2022 Nov 1;92(9):739-749. doi: 10.1016/j.biopsych.2022.05.012. Epub 2022 May 17.

Arena C, Gado F, Di Cesare Mannelli L, Cervetto C, Carpi S, Reynoso-Moreno I, Polini B, Vallini E, Chicca S, Lucarini E, Bertini S, D'Andrea F, Digiacomo M, Poli G, Tuccinardi T, Macchia M, Gertsch J, Marcoli M, Nieri P, Ghelardini C, Chicca A, Manera C., The endocannabinoid system dual-target ligand N-cycloheptyl-1,2-dihydro-5-bromo-1-(4-fluorobenzyl)-6-methyl-2-oxo-pyridine-3-carboxamide improves disease severity in a mouse model of multiple sclerosis, Eur J Med Chem. 2020 Dec 15;208:112858. doi: 10.1016/j.ejmech.2020.112858. Epub 2020 Sep 29.

Lainiola, Mira; Hietala, Lana; Linden, Anni-Maija; Aitta-Aho, Teemu;, The lack of conditioned place preference, but unaltered stimulatory and ataxic effects of alcohol in mGluR3-KO mice., Journal of psychopharmacology (Oxford, England) Vol.33, 2019

Williams, K. C., Renthal, N. E., Gerard, R. D., & Mendelson, C. R. (2012)., The microRNA (miR)-199a/214 cluster mediates opposing effects of progesterone and estrogen on uterine contractility during pregnancy and labor., Molecular Endocrinology (Baltimore, Md.), 26(11), 1857-1867. doi:10.1210/me.2012-1199 [doi]

Liu, B., Hassan, Z., Amisten, S., King, A. J., Bowe, J. E., Huang, G. C., . . . Persaud, S. J. (2013)., The novel chemokine receptor, G-protein-coupled receptor 75, is expressed by islets and is coupled to stimulation of insulin secretion and improved glucose homeostasis., Diabetologia, 56(11), 2467-2476. doi:10.1007/s00125-013-3022-x [doi]

Hill, R., Disney, A., Conibear, A., Sutcliffe, K., Dewey, W., Husbands, S., . . . Henderson, G. (2018)., The novel mu-opioid receptor agonist PZM21 depresses respiration and induces tolerance to antinociception., British Journal of Pharmacology, 175(13), 2653-2661. doi:10.1111/bph.14224 [doi]

ainter, George R; Bowen, Richard A; Bluemling, Gregory R; DeBergh, John; Edpuganti, Vindhya; Gruddanti, Prabhakar R; Guthrie, David B; Hager, Michael; Kuiper, Damien L; Lockwood, Mark A; Mitchell, Deborah G; Natchus, Michael G; Sticher, Zachary M; Kolykhalov, Alexander A;, The prophylactic and therapeutic activity of a broadly active ribonucleoside analog in a murine model of intranasal venezuelan equine encephalitis virus infection., Antiviral research Vol.171, 2019

Painter, George R; Bowen, Richard A; Bluemling, Gregory R; DeBergh, John; Edpuganti, Vindhya; Gruddanti, Prabhakar R; Guthrie, David B; Hager, Michael; Kuiper, Damien L; Lockwood, Mark A; Mitchell, Deborah G; Natchus, Michael G; Sticher, Zachary M; Kolykhalov, Alexander A;, The prophylactic and therapeutic activity of a broadly active ribonucleoside analog in a murine model of intranasal venezuelan equine encephalitis virus infection., Antiviral research Vol.171, 2019

Chuderland, D., Ben-Ami, I., Kaplan-Kraicer, R., Grossman, H., Ron-El, R., & Shalgi, R. (2013)., The role of pigment epithelium-derived factor in the pathophysiology and treatment of ovarian hyperstimulation syndrome in mice, The Journal of Clinical Endocrinology and Metabolism, 98(2), E258-66. doi:10.1210/jc.2012-3037 [doi]

Borgonetti V, Mugnaini C, Corelli F, Galeotti N., The Selective CB2 Agonist COR167 Reduced Symptoms in a Mice Model of Trauma-Induced Peripheral Neuropathy through HDAC-1 Inhibition., Biomedicines. 2023 May 26;11(6). pii: 1546. doi: 10.3390/biomedicines11061546.

Yifa, Oren; Weisinger, Karen; Bassat, Elad; Li, Hanjun; Kain, David; Barr, Haim; Kozer, Noga; Genzelinakh, Alexander; Rajchman, Dana; Eigler, Tamar; Umansky, Kfir Baruch; Lendengolts, Daria; Brener, Ori; Bursac, Nenad; Tzahor, Eldad, The small molecule Chicago Sky Blue promotes heart repair following myocardial infarction in mice, JCI insight Vol.4, 2019

Lobo B, Tramullas M, Finger BC, Lomasney KW, Beltran C, Clarke G, Santos J, Hyland NP, Dinan TG, Cryan JF., The Stressed Gut: Region-specific Immune and Neuroplasticity Changes in Response to Chronic Psychosocial Stress., J Neurogastroenterol Motil. 2023 Jan 30;29(1):72-84. doi: 10.5056/jnm22009.

Qiu X, Liang X, Llongueras JP, Cunningham C, MÃ¼ller U., The tetraspan LHFPL5 is critical to establish maximal force sensitivity of the mechanotransduction channel of cochlear hair cells., Cell Rep. 2023 Mar 28;42(3):112245. doi: 10.1016/j.celrep.2023.112245. Epub 2023 Mar 13.

Cohen, Jonathan; Raviv, Shaul; Adir, Orit; Padmanabhan, Krishnanand; Soffer, Arad; Luxenburg, Chen;, The Wave complex controls epidermal morphogenesis and proliferation by suppressing Wnt-Sox9 signaling., The Journal of cell biology Vol.218, 2019

Ali SM, Chen P, Sheikh S, Ahmad A, Ahmad M, Paithankar M, Desai B, Patel P, Khan M, Chaturvedi A, Patel R, Panchal DT, Shah K, Chavda V, Saboo BD, Patel A, Ahmad I., Thymoquinone with Metformin Decreases Fasting, Post Prandial Glucose, and HbA1c in Type 2 Diabetic Patients, Drug Res (Stuttg). 2021 Jul;71(6):302-306. doi: 10.1055/a-1388-5415. Epub 2021 Mar 8.

Padmanabhan K, Grobe H, Cohen J, Soffer A, Mahly A, Adir O, Zaidel-Bar R, Luxenburg C., Thymosin Î˛4 is essential for adherens junction stability and epidermal planar cell polarity, Development. 2020 Dec 11;147(23):dev193425. doi: 10.1242/dev.193425.

Mayshar Y, Raz O, Cheng S, Ben-Yair R, Hadas R, Reines N, Mittnenzweig M, Ben-Kiki O, Lifshitz A, Tanay A, Stelzer Y., Time-aligned hourglass gastrulation models in rabbit and mouse., Cell. 2023 Jun 8;186(12):2610-2627.e18. doi: 10.1016/j.cell.2023.04.037. Epub 2023 May 19.

Ribas-Aulinas F, Parra-Vargas M, Ramon-Krauel M, Diaz R, Lerin C, Cambras T, Jimenez-Chillaron JC., Time-Restricted Feeding during Puberty Ameliorates Adiposity and Prevents Hepatic Steatosis in a Mouse Model of Childhood Obesity, Nutrients. 2021 Oct 13;13(10):3579. doi: 10.3390/nu13103579.

Cunningham CL, Qiu X, Wu Z, Zhao B, Peng G, Kim YH, Lauer A, MĂźller U., TMIE Defines Pore and Gating Properties of the Mechanotransduction Channel of Mammalian Cochlear Hair Cells, Neuron. 2020 Jul 8;107(1):126-143.e8. doi: 10.1016/j.neuron.2020.03.033. Epub 2020 Apr 27.

Skepper CK, Armstrong D, Balibar CJ, Bauer D, Bellamacina C, Benton BM, Bussiere D, De Pascale G, De Vicente J, Dean CR, Dhumale B, Fisher LM, Fuller J, Fulsunder M, Holder LM, Hu C, Kantariya B, Lapointe G, Leeds JA, Li X, Lu P, Lvov A, Ma S, Madhavan S, Malekar S, McKenney D, Mergo W, Metzger L, Moser HE, Mutnick D, Noeske J, Osborne C, Patel A, Patel D, Patel T, Prajapati K, Prosen KR, Reck F, Richie DL, Rico A, Sanderson MR, Satasia S, Sawyer WS, Selvarajah J, Shah N, Shanghavi K, Shu W, Thompson KV, Traebert M, Vala A, Vala L, Veselkov DA, Vo J, Wang M, Widya M, Williams SL, Xu Y, Yue Q, Zang R, Zhou B, Rivkin A., Topoisomerase Inhibitors Addressing Fluoroquinolone Resistance in Gram-Negative Bacteria, J Med Chem. 2020 Jul 23;63(14):7773-7816. doi: 10.1021/acs.jmedchem.0c00347. Epub 2020 Jul 7.

Rouquette, Marie; Ser-Le Roux, Karine; Polrot, M?lanie; Bourgaux, Claudie; Michel, Jean-Philippe; Testard, Fabienne; Gobeaux, Fr?d?ric; Lepetre-Mouelhi, Sinda;, Towards a clinical application of freeze-dried squalene-based nanomedicines., Journal of drug targeting Vol.27,

Rouquette, Marie; Ser-Le Roux, Karine; Polrot, MĂŠlanie; Bourgaux, Claudie; Michel, Jean-Philippe; Testard, Fabienne; Gobeaux, FrĂŠdĂŠric; Lepetre-Mouelhi, Sinda;, Towards a clinical application of freeze-dried squalene-based nanomedicines., Journal of drug targeting Vol.27,

Voronov, D., Gromova, A., Liu, D., Zoukhri, D., Medvinsky, A., Meech, R., & Makarenkova, H. P. (2013)., Transcription factors Runx1 to 3 are expressed in the lacrimal gland epithelium and are involved in regulation of gland morphogenesis and regeneration., Investigative Ophthalmology & Visual Science, 54(5), 3115-3125. doi:10.1167/iovs.13-11791 [doi]

Zhang C, Shi Y, Burch M, Olthoff B, Ericsson AC, Franklin CL., Transfer efficiency and impact on disease phenotype of differing methods of gut microbiota transfer, Sci Rep. 2022 Nov 15;12(1):19621. doi: 10.1038/s41598-022-24014-x.

Bohr A, Tsapis N, Foged C, Andreana I, Yang M, Fattal E., Treatment of acute lung inflammation by pulmonary delivery of anti-TNF-Îą siRNA with PAMAM dendrimers in a murine model, Eur J Pharm Biopharm. 2020 Nov;156:114-120. doi: 10.1016/j.ejpb.2020.08.009. Epub 2020 Aug 13.

Paterniti I, Filippone A, Naletova I, Greco V, Sciuto S, Esposito E, Cuzzocrea S, Rizzarelli E., Trehalose-Carnosine Prevents the Effects of Spinal Cord Injury Through Regulating Acute Inflammation and Zinc(II) Ion Homeostasis, Cell Mol Neurobiol. 2022 Sep 19. doi: 10.1007/s10571-022-01273-w. Online ahead of print.

Paterniti I, Filippone A, Naletova I, Greco V, Sciuto S, Esposito E, Cuzzocrea S, Rizzarelli E., Trehalose-Carnosine Prevents the Effects of Spinal Cord Injury Through Regulating Acute Inflammation and Zinc(II) Ion Homeostasis., Cell Mol Neurobiol. 2023 May;43(4):1637-1659. doi: 10.1007/s10571-022-01273-w. Epub 2022 Sep 19.

Ardizzone A, Filippone A, Mannino D, Scuderi SA, Casili G, Lanza M, Cucinotta L, Campolo M, Esposito E., Ulva pertusa, a Marine Green Alga, Attenuates DNBS-Induced Colitis Damage via NF-κB/Nrf2/SIRT1 Signaling Pathways, J Clin Med. 2022 Jul 25;11(15):4301. doi: 10.3390/jcm11154301.

Shavit-Stein E, Gerasimov A, Aharoni S, Gofrit SG, Pikus E, Pick CG, Maggio N., Unexpected role of stress as a possible resilience mechanism upon mild traumatic brain injury (mTBI) in mice, Mol Cell Neurosci. 2021 Mar;111:103586. doi: 10.1016/j.mcn.2020.103586. Epub 2021 Jan 4.

Camuto C, Pellegrini S, De-Giorgio F, de la Torre X, Marti M, Mazzarino M, Botrč F., Urinary excretion profile of methiopropamine in mice following intraperitoneal administration: A liquid chromatography-tandem mass spectrometry investigation, Drug Test Anal. 2021 Jan;13(1):91-100. doi: 10.1002/dta.2900. Epub 2020 Aug 7.

Dedoni S, Marras L, Olianas MC, Ingianni A, Onali P., Valproic acid upregulates the expression of the p75NTR/sortilin receptor complex to induce neuronal apoptosis, Apoptosis. 2020 Oct;25(9-10):697-714. doi: 10.1007/s10495-020-01626-0.

Dhingra, S., Andes, D., & Calvo, A. M. (2012)., VeA regulates conidiation, gliotoxin production, and protease activity in the opportunistic human pathogen aspergillus fumigatus, Eukaryotic Cell, 11(12), 1531-1543. doi:10.1128/EC.00222-12 [doi]

Laajala M, Zwaagstra M, Martikainen M, Nekoua MP, Benkahla M, Sane F, Gervais E, Campagnola G, Honkimaa A, Sioofy-Khojine AB, HyÃ¶ty H, Ojha R, Bailliot M, Balistreri G, Peersen O, Hober D, Van Kuppeveld F, MarjomÃ¤ki V., Vemurafenib Inhibits Acute and Chronic Enterovirus Infection by Affecting Cellular Kinase Phosphatidylinositol 4-Kinase Type IIIβ, Microbiol Spectr. 2023 Aug 17;11(4):e0055223. doi: 10.1128/spectrum.00552-23. Epub 2023 Jul 12.

Hickman DL., Wellbeing of Mice Euthanized with Carbon Dioxide in Their Home Cage as Compared with an Induction Chamber, J Am Assoc Lab Anim Sci. 2020 Oct 6. doi: 10.30802/AALAS-JAALAS-20-000055. Online ahead of print.

Hickman DL., Wellbeing of Mice Euthanized with Carbon Dioxide in Their Home Cage as Compared with an Induction Chamber, J Am Assoc Lab Anim Sci. 2021 Jan 1;60(1):72-76. doi: 10.30802/AALAS-JAALAS-20-000055. Epub 2020 Oct 6.

Borgonetti V, López V, Galeotti N., Ylang-ylang (Cananga odorata (Lam.) Hook. f. & Thomson) essential oil reduced neuropathic-pain and associated anxiety symptoms in mice, J Ethnopharmacol. 2022 Aug 10;294:115362. doi: 10.1016/j.jep.2022.115362. Epub 2022 May 10.

Chen YY, Chen S, Ok K, Duncan FE, O'Halloran TV, Woodruff TK., Zinc dynamics regulate early ovarian follicle development., J Biol Chem. 2023 Jan;299(1):102731. doi: 10.1016/j.jbc.2022.102731. Epub 2022 Nov 22.

Borgonetti V, Governa P, Manetti F, Galeotti N., Zingiberene, a non-zinc-binding class I HDAC inhibitor: A novel strategy for the management of neuropathic pain., Phytomedicine. 2023 Mar;111:154670. doi: 10.1016/j.phymed.2023.154670. Epub 2023 Jan 13.

Bajaj, G., Van Alstine, W. G., & Yeo, Y. (2012)., Zwitterionic chitosan derivative, a new biocompatible pharmaceutical excipient, prevents endotoxin-mediated cytokine release., null

Infectious disease

Guo XP, Yan HQ, Yang W, Yin Z, Vadyvaloo V, Zhou D, Sun YC., A frameshift in Yersinia pestis rcsD alters canonical Rcs signalling to preserve flea-mammal plague transmission cycles., Elife. 2023 Apr 3;12. pii: e83946. doi: 10.7554/eLife.83946.

Sauder AB, Kendall MM., A pathogen-specific sRNA influences enterohemorrhagic Escherichia coli fitness and virulence in part by direct interaction with the transcript encoding the ethanolamine utilization regulatory factor EutR, Nucleic Acids Res. 2021 Nov 8;49(19):10988-11004. doi: 10.1093/nar/gkab863.

Andes DR, Nett JE., Analysis of Candida Antifungal Resistance Using Animal Infection Models., Methods Mol Biol. 2023;2658:225-238. doi: 10.1007/978-1-0716-3155-3_16.

Szebenyi C, Gu Y, Gebremariam T, KocsubÃ© S, Kiss-VetrÃ¡b S, JÃ¡ger O, Patai R, SpisÃ¡k K, Sinka R, Binder U, Homa M, VÃ¡gvÃ¶lgyi C, Ibrahim AS, Nagy G, Papp T., cotH Genes Are Necessary for Normal Spore Formation and Virulence in Mucor lusitanicus., mBio. 2023 Feb 28;14(1):e0338622. doi: 10.1128/mbio.03386-22. Epub 2023 Jan 10.

Heida R, Akkerman R, Jacob Silva PH, Lakerveld AJ, Ortiz D, Bigogno C, Gasbarri M, van Kasteren PB, Stellacci F, Frijlink HW, Huckriede ALW, Hinrichs WLJ., Development of an inhalable antiviral powder formulation against respiratory syncytial virus., J Control Release. 2023 May;357:264-273. doi: 10.1016/j.jconrel.2023.03.059. Epub 2023 Apr 5.

Casselli T, Tourand Y, Gura K, Stevenson B, ZÃ¼ckert WR, Brissette CA., Endogenous Linear Plasmids lp28-4 and lp25 Are Required for Infectivity and Restriction Protection in the Lyme Disease Spirochete Borrelia mayonii., Infect Immun. 2023 Mar 15;91(3):e0006123. doi: 10.1128/iai.00061-23. Epub 2023 Feb 28.

Thiriot J, Liang Y, Fisher J, Walker DH, Soong L., Host transcriptomic profiling of CD-1 outbred mice with severe clinical outcomes following infection with Orientia tsutsugamushi, PLoS Negl Trop Dis. 2022 Nov 23;16(11):e0010459. doi: 10.1371/journal.pntd.0010459. eCollection 2022 Nov.

Dabbah-Assadi F, Rashid S, Golani I, Rubinstein A, Doron R, Alon D, Palzur E, Beloosesky R, Shamir A., Long-term effects of prophylactic MgSO(4) in maternal immune activation rodent model at adolescence and adulthood, J Neurosci Res. 2023 Mar;101(3):316-326. doi: 10.1002/jnr.25148. Epub 2022 Nov 26.

Gao J, Su Y, Wang Z., Remote Co-loading of amphipathic acid drugs in neutrophil nanovesicles infilled with cholesterol mitigates lung bacterial infection and inflammation., Biomaterials. 2023 May;296:122071. doi: 10.1016/j.biomaterials.2023.122071. Epub 2023 Feb 28.

Walker JM, Sundarasivarao PYK, Thornton JM, Sochacki K, Rodriguez A, Spur BW, Acharya NK, Yin K., Resolvin D2 promotes host defense in a 2 - hit model of sepsis with secondary lung infection, Prostaglandins Other Lipid Mediat. 2022 Apr;159:106617. doi: 10.1016/j.prostaglandins.2022.106617. Epub 2022 Jan 8.

Oncology

Tremmel, Lisa; Rho, Okkyung; Slaga, Thomas J; DiGiovanni, John;, Inhibition of skin tumor promotion by TPA using a combination of topically applied ursolic acid and curcumin., Molecular carcinogenesis Vol.58, 2019

de la Fuente, M., Jones, M. C., Santander-Ortega, M. J., Mirenska, A., Marimuthu, P., Uchegbu, I., & Schatzlein, A. (2015)., A nano-enabled cancer-specific ITCH RNAi chemotherapy booster for pancreatic cancer., Nanomedicine : Nanotechnology, Biology, and Medicine, 11(2), 369-377. doi:10.1016/j.nano.2014.09.010 [doi]

Qiu, X., Liang, Y., Sellers, R. S., Perez-Soler, R., & Zou, Y. (2014)., Aerosol azacytidine inhibits orthotopic lung cancers in mice through its DNA demethylation and gene reactivation effects., PloS One, 9(10), e109874. doi:10.1371/journal.pone.0109874 [doi]

Frosina, G., Profumo, A., Marubbi, D., Marcello, D., Ravetti, J. L., & Daga, A. (2018)., ATR kinase inhibitors NVP-BEZ235 and AZD6738 effectively penetrate the brain after systemic administration, Radiation Oncology (London, England), 13(1), 76-018-1020-3. doi:10.1186/s13014-018-1020-3 [doi]

Airouche S, Beltrami V, Fleury S, Batard T, Bordas-Le Floch V, Stegmann T, Amacker M, Kettner A, Mascarell L., Bet v 1 contiguous overlapping peptides anchored to virosomes with TLR4 agonist enhance immunotherapy efficacy in mice, Clin Exp Allergy. 2021 Feb;51(2):339-349. doi: 10.1111/cea.13814. Epub 2021 Jan 6.

Oliveira, H., Lopes, T., Almeida, T., Pereira Mde, L., & Santos, C. (2012), Cadmium-induced genetic instability in mice testis, Human & Experimental Toxicology, 31(12), 1228-1236. doi:10.1177/0960327112445937 [doi]

Smith, M. C., Mader, M. M., Cook, J. A., Iversen, P., Ajamie, R., Perkins, E., . . . Wacheck, V. (2016)., Characterization of LY3023414, a novel PI3K/mTOR dual inhibitor eliciting transient target modulation to impede tumor growth, Molecular Cancer Therapeutics, 15(10), 2344-2356. doi:1535-7163.MCT-15-0996 [pii]

Aviello, G., Romano, B., Borrelli, F., Capasso, R., Gallo, L., Piscitelli, F., . . . Izzo, A. A. (2012)., Chemopreventive effect of the non-psychotropic phytocannabinoid cannabidiol on experimental colon cancer., Journal of Molecular Medicine (Berlin, Germany), 90(8), 925-934. doi:10.1007/s00109-011-0856-x [doi]

Gridley, D. S., Freeman, T. L., Makinde, A. Y., Wroe, A. J., Luo-Owen, X., Tian, J., . . . Pecaut, M. J. (2011), Comparison of proton and electron radiation effects on biological responses in liver, spleen and blood., International Journal of Radiation Biology, 87(12), 1173-1181. doi:10.3109/09553002.2011.624393 [doi]

Arantes-Rodrigues, R., Pinto-Leite, R., da Costa, R. G., Colaco, A., Lopes, C., & Oliveira, P. (2013)., Cytogenetic characterization of an N-butyl-N-(4-hydroxybutyl) nitrosamine-induced mouse papillary urothelial carcinoma., Tumour Biology : The Journal of the International Society for Oncodevelopmental Biology and Medicine, 34(5), 2691-2696. doi:10.1007/s13277-013-0820-1 [doi]

Santos, N. P., Oliveira, P. A., Arantes-Rodrigues, R., Faustino-Rocha, A. I., Colaco, A., Lopes, C., & Gil da Costa, R. M. (2014)., Cytokeratin 7/19 expression in N-diethylnitrosamine-induced mouse hepatocellular lesions: Implications for histogenesis., International Journal of Experimental Pathology, 95(3), 191-198. doi:10.1111/iep.12082 [doi]

Sengar, P., Juarez, P., Verdugo-Meza, A., Arellano, D. L., Jain, A., Chauhan, K., . . . Fournier, P. G. J. (2018)., Development of a functionalized UV-emitting nanocomposite for the treatment of cancer using indirect photodynamic therapy., Journal of Nanobiotechnology, 16(1), 19-018-0344-3. doi:10.1186/s12951-018-0344-3 [doi]

Nachliely, Matan; Trachtenberg, Aviram; Khalfin, Boris; Nalbandyan, Karen; Cohen-Lahav, Merav; Yasuda, Kaori; Sakaki, Toshiyuki; Kutner, Andrzej; Danilenko, Michael;, Dimethyl fumarate and vitamin D derivatives cooperatively enhance VDR and Nrf2 signaling in differentiating AML cells in vitro and inhibit leukemia progression in a xenograft mouse model., The Journal of steroid biochemistry and molecular biology Vol.188, 2019

Procopiou G, Jackson PJM, di Mascio D, Auer JL, Pepper C, Rahman KM, Fox KR, Thurston DE., DNA sequence-selective G-A cross-linking ADC payloads for use in solid tumour therapies, Commun Biol. 2022 Jul 29;5(1):741. doi: 10.1038/s42003-022-03633-0.

Beziere, N., Lozano, N., Nunes, A., Salichs, J., Queiros, D., Kostarelos, K., & Ntziachristos, V. (2015)., Dynamic imaging of PEGylated indocyanine green (ICG) liposomes within the tumor microenvironment using multi-spectral optoacoustic tomography (MSOT), Biomaterials, 37, 415-424. doi:10.1016/j.biomaterials.2014.10.014 [doi]

Vasconcelos-Nobrega, C., Costa, C., Vala, H., Colaco, A., Santos, L., Lopes, C., & Oliveira, P. A. (2013), E-cadherin and beta-catenin expression during urothelial carcinogenesis induced by N-butyl-N-(4-hydroxybutyl) nitrosamine in mice., Urologia Internationalis, 91(4), 462-466. doi:10.1159/000348329 [doi]

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Cho, J., Rho, O., Junco, J., Carbajal, S., Siegel, D., Slaga, T. J., & DiGiovanni, J. (2015)., Effect of combined treatment with ursolic acid and resveratrol on skin tumor promotion by 12-O-tetradecanoylphorbol-13-acetate., Cancer Prevention Research (Philadelphia, Pa.), 8(9), 817-825. doi:10.1158/1940-6207.CAPR-15-0098 [doi]

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Bagdadi N, Sawaied A, AbuMadighem A, Lunenfeld E, Huleihel M., The Expression Levels and Cellular Localization of Pigment Epithelium Derived Factor (PEDF) in Mouse Testis: Its Possible Involvement in the Differentiation of Spermatogonial Cells, Int J Mol Sci. 2021 Jan 24;22(3):1147. doi: 10.3390/ijms22031147.

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Toxicology

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Arguelles-Velazquez, N., Alvarez-Gonzalez, I., Madrigal-Bujaidar, E., & Chamorro-Cevallos, G. (2013)., Amelioration of cadmium-produced teratogenicity and genotoxicity in mice given arthrospira maxima (spirulina) treatment., Evidence-Based Complementary and Alternative Medicine : ECAM, 2013, 604535. doi:10.1155/2013/604535 [doi]

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Xiao, J., Li, Y., Gressitt, K. L., He, H., Kannan, G., Schultz, T. L., . . . Severance, E. G. (2016)., Cerebral complement C1q activation in chronic toxoplasma infection, Brain, Behavior, and Immunity, 58, 52-56. doi:S0889-1591(16)30100-3 [pii]

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D'Amico R, Di Paola D, Impellizzeri D, Genovese T, Fusco R, Peritore AF, Gugliandolo E, Crupi R, Interdonato L, Cuzzocrea S, Di Paola R, Siracusa R, Cordaro M., Chronic Exposure to Endocrine Disruptor Vinclozolin Leads to Lung Damage via Nrf2-Nf-kb Pathway Alterations, Int J Mol Sci. 2022 Sep 26;23(19):11320. doi: 10.3390/ijms231911320.

Di Paola D, D'Amico R, Genovese T, Siracusa R, Cordaro M, Crupi R, Peritore AF, Gugliandolo E, Interdonato L, Impellizzeri D, Fusco R, Cuzzocrea S, Di Paola R., Chronic Exposure to Vinclozolin Induced Fibrosis, Mitochondrial Dysfunction, Oxidative Stress, and Apoptosis in Mice Kidney, Int J Mol Sci. 2022 Sep 25;23(19):11296. doi: 10.3390/ijms231911296.

Cho, N., Lee, K. Y., Huh, J., Choi, J. H., Yang, H., Jeong, E. J., . . . Sung, S. H. (2013)., Cognitive-enhancing effects of rhus verniciflua bark extract and its active flavonoids with neuroprotective and anti-inflammatory activities, Food and Chemical Toxicology : An International Journal Published for the British Industrial Biological Research Association, 58, 355-361. doi:10.1016/j.fct.2013.05.007 [doi]

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Mao, X. W., Mekonnen, T., Kennedy, A. R., & Gridley, D. S. (2011)., Differential expression of oxidative stress and extracellular matrix remodeling genes in low- or high-dose-rate photon-irradiated skin., Radiation Research, 176(2), 187-197. doi:10.1667/RR2493.1 [pii]

Hinkley, G. K., Carpinone, P. L., Munson, J. W., Powers, K. W., & Roberts, S. M. (2015)., Differential interferences with clinical chemistry assays by gold nanorods, and gold and silica nanospheres., Nanotoxicology, 9(1), 116-125. doi:10.3109/17435390.2014.894151 [doi]

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Ben Aharon, I., Bar Joseph, H., Tzabari, M., Shenkman, B., Farzam, N., Levi, M., . . . Savion, N. (2013)., Doxorubicin-induced vascular toxicity--targeting potential pathways may reduce procoagulant activity, PloS One, 8(9), e75157. doi:10.1371/journal.pone.0075157 [doi]

Ramesh, D., Gamage, T. F., Vanuytsel, T., Owens, R. A., Abdullah, R. A., Niphakis, M. J., . . . Lichtman, A. H. (2013)., Dual inhibition of endocannabinoid catabolic enzymes produces enhanced antiwithdrawal effects in morphine-dependent mice., . Neuropsychopharmacology : Official Publication of the American College of Neuropsychopharmacology, 38(6), 1039-1049. doi:10.1038/npp.2012.269 [doi]

Negus, S. S., Neddenriep, B., Altarifi, A. A., Carroll, F. I., Leitl, M. D., & Miller, L. L. (2015)., Effects of ketoprofen, morphine, and kappa opioids on pain-related depression of nesting in mice., Pain, 156(6), 1153-1160. doi:10.1097/j.pain.0000000000000171 [doi]

Venerosi, A., Tait, S., Stecca, L., Chiarotti, F., De Felice, A., Cometa, M. F., . . . Ricceri, L. (2015)., Effects of maternal chlorpyrifos diet on social investigation and brain neuroendocrine markers in the offspring - a mouse study., Environmental Health : A Global Access Science Source, 14, 32-015-0019-6. doi:10.1186/s12940-015-0019-6 [doi]

Bagdas, D., Muldoon, P. P., Zhu, A. Z., Tyndale, R. F., & Damaj, M. I. (2014)., Effects of methoxsalen, a CYP2A5/6 inhibitor, on nicotine dependence behaviors in mice., Neuropharmacology, 85, 67-72. doi:10.1016/j.neuropharm.2014.05.006 [doi]

Murphy, E. A., Davis, J. M., Brown, A. S., Carmichael, M. D., Ghaffar, A., & Mayer, E. P. (2012)., Effects of oat beta-glucan on the macrophage cytokine response to herpes simplex virus 1 infection in vitro., Journal of Interferon & Cytokine Research : The Official Journal of the International Society for Interferon and Cytokine Research, 32(8), 362-367. doi:10.1089/jir.2011.0067 [doi]

Wiley, J. L., Walentiny, D. M., Wright, M. J.,Jr, Beardsley, P. M., Burston, J. J., Poklis, J. L., . . . Vann, R. E. (2014)., Endocannabinoid contribution to Delta9-tetrahydrocannabinol discrimination in rodents., European Journal of Pharmacology, 737, 97-105. doi:10.1016/j.ejphar.2014.05.013 [doi]

Corli G, Tirri M, Bilel S, Giorgetti A, Bernardi T, Boccuto F, Borsari M, Giorgetti R, Marti M., Ethanol enhances JWH-018-induced impairment of sensorimotor and memory functions in mice: From preclinical evidence to forensic implication in Driving Under the Influence of Drugs., Drug Alcohol Depend. 2023 Jun 1;247:109888. doi: 10.1016/j.drugalcdep.2023.109888. Epub 2023 Apr 18.

Genovese T, Duranti A, D'Amico R, Fusco R, Impellizzeri D, Peritore AF, Crupi R, Gugliandolo E, Cuzzocrea S, Di Paola R, Siracusa R, Cordaro M., Fatty Acid Amide Hydrolase (FAAH) Inhibition Plays a Key Role in Counteracting Acute Lung Injury, Int J Mol Sci. 2022 Mar 3;23(5):2781. doi: 10.3390/ijms23052781.

AkgĂźn E, Lunzer MM, Tian D, Ansonoff M, Pintar J, Bruce D, Hawkinson JE, Wilcox GL, Portoghese PS., FBNTI, a DOR-Selective Antagonist That Allosterically Activates MOR within a MOR-DOR Heteromer, Biochemistry. 2020 Sep 20. doi: 10.1021/acs.biochem.0c00498. Online ahead of print.

Li, M., Holmes, V., Zhou, Y., Ni, H., Sanzari, J. K., Kennedy, A. R., & Weissman, D. (2014)., Hindlimb suspension and SPE-like radiation impairs clearance of bacterial infections., PloS One, 9(1), e85665. doi:10.1371/journal.pone.0085665 [doi]

Santos, N. P., Pereira, I. C., Pires, M. J., Lopes, C., Andrade, R., Oliveira, M. M., . . . Oliveira, P. A. (2012)., Histology, bioenergetics and oxidative stress in mouse liver exposed to N-diethylnitrosamine, In Vivo (Athens, Greece), 26(6), 921-929. doi:26/6/921 [pii]

Miguel-Blanco, C., Molina, I., Bardera, A. I., Diaz, B., de Las Heras, L., Lozano, S., . . . Herreros, E. (2017)., Hundreds of dual-stage antimalarial molecules discovered by a functional gametocyte screen., Nature Communications, 8, 15160. doi:10.1038/ncomms15160 [doi]

Gear, R. B., & Belcher, S. M. (2017)., Impacts of bisphenol A and ethinyl estradiol on male and female CD-1 mouse spleen., Scientific Reports, 7(1), 856-017-00961-8. doi:10.1038/s41598-017-00961-8 [doi]

Krishnan Natesan, S., Wu, W., Cutright, J. L., & Chandrasekar, P. H. (2012)., In vitro-in vivo correlation of voriconazole resistance due to G448S mutation (cyp51A gene) in aspergillus fumigatus., Diagnostic Microbiology and Infectious Disease, 74(3), 272-277. doi:10.1016/j.diagmicrobio.2012.06.030 [doi]

Bar-Joseph, H., Ben-Aharon, I., Tzabari, M., Tsarfaty, G., Stemmer, S. M., & Shalgi, R. (2011)., In vivo bioimaging as a novel strategy to detect doxorubicin-induced damage to gonadal blood vessels., PloS One, 6(9), e23492. doi:10.1371/journal.pone.0023492 [doi]

Ignatowska-Jankowska, B. M., Ghosh, S., Crowe, M. S., Kinsey, S. G., Niphakis, M. J., Abdullah, R. A., . . . Lichtman, A. H. (2014), In vivo characterization of the highly selective monoacylglycerol lipase inhibitor KML29: Antinociceptive activity without cannabimimetic side effects., British Journal of Pharmacology, 171(6), 1392-1407. doi:10.1111/bph.12298 [doi]

Garcia-Rodriguez Mdel, C., Hernandez-Cortes, L. M., & Altamirano-Lozano, M. A. (2016), In vivo effects of vanadium pentoxide and antioxidants (ascorbic acid and alpha-tocopherol) on apoptotic, cytotoxic, and genotoxic damage in peripheral blood of mice, Oxidative Medicine and Cellular Longevity, 2016, 6797851. doi:10.1155/2016/6797851 [doi]

Boydston JA, Yeager JJ, Taylor JR, Dabisch PA., Influence of aerodynamic particle size on botulinum neurotoxin potency in mice, Inhal Toxicol. 2021 Jan;33(1):1-7. doi: 10.1080/08958378.2020.1851327. Epub 2021 Jan 6.

Muldoon, P. P., Chen, J., Harenza, J. L., Abdullah, R. A., Sim-Selley, L. J., Cravatt, B. F., . . . Damaj, M. I. (2015)., Inhibition of monoacylglycerol lipase reduces nicotine withdrawal., British Journal of Pharmacology, 172(3), 869-882. doi:10.1111/bph.12948 [doi]

Izzo, A. A., Capasso, R., Aviello, G., Borrelli, F., Romano, B., Piscitelli, F., . . . Di Marzo, V. (2012)., Inhibitory effect of cannabichromene, a major non-psychotropic cannabinoid extracted from cannabis sativa, on inflammation-induced hypermotility in mice., British Journal of Pharmacology, 166(4), 1444-1460. doi:10.1111/j.1476-5381.2012.01879.x [doi]

Toker, L., Bersudsky, Y., Plaschkes, I., Chalifa-Caspi, V., Berry, G. T., Buccafusca, R., . . . Agam, G. (2014)., Inositol-related gene knockouts mimic lithium's effect on mitochondrial function, Neuropsychopharmacology : Official Publication of the American College of Neuropsychopharmacology, 39(2), 319-328. doi:10.1038/npp.2013.194 [doi]

Lewis BE, Mulka A, Mao L, Sharafieh R, Qiao Y, Kesserwan S, Wu R, Kreutzer D, Klueh U., Insulin Derived Fibrils Induce Cytotoxicity in vitro and Trigger Inflammation in Murine Models, J Diabetes Sci Technol. 2021 Jul 21:19322968211033868. doi: 10.1177/19322968211033868. Online ahead of print.

Zhou, Y., Ni, H., Balint, K., Sanzari, J. K., Dentchev, T., Diffenderfer, E. S., . . . Weissman, D. (2014)., Ionizing radiation selectively reduces skin regulatory T cells and alters immune function., PloS One, 9(6), e100800. doi:10.1371/journal.pone.0100800 [doi]

Galli CL, Cinelli S, Ciliutti P, Melzi G, Marinovich M., Lack of in vivo genotoxic effect of dried whole Aloe ferox juice, Toxicol Rep. 2021 Aug 3;8:1471-1474. doi: 10.1016/j.toxrep.2021.07.023. eCollection 2021.

Sorrell, M. E., & Hauser, K. F. (2014)., Ligand-gated purinergic receptors regulate HIV-1 tat and morphine related neurotoxicity in primary mouse striatal neuron-glia co-cultures. Journal of Neuroimmune Pharmacology, The Official Journal of the Society on NeuroImmune Pharmacology, 9(2), 233-244. doi:10.1007/s11481-013-9507-z [doi]

Akgun, E., Javed, M. I., Lunzer, M. M., Smeester, B. A., Beitz, A. J., & Portoghese, P. S. (2013)., Ligands that interact with putative MOR-mGluR5 heteromer in mice with inflammatory pain produce potent antinociception., Proceedings of the National Academy of Sciences of the United States of America, 110(28), 11595-11599. doi:10.1073/pnas.1305461110 [doi]

Wiederhold, N. P., Najvar, L. K., Bocanegra, R., Kirkpatrick, W. R., Sorrell, T. C., & Patterson, T. F. (2013)., Limited activity of miltefosine in murine models of cryptococcal meningoencephalitis and disseminated cryptococcosis, Antimicrobial Agents and Chemotherapy, 57(2), 745-750. doi:10.1128/AAC.01624-12 [doi]

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Capasso, R., Aviello, G., Romano, B., Borrelli, F., De Petrocellis, L., Di Marzo, V., & Izzo, A. A. (2012)., Modulation of mouse gastrointestinal motility by allyl isothiocyanate, a constituent of cruciferous vegetables (brassicaceae): Evidence for TRPA1-independent effects., British Journal of Pharmacology, 165(6), 1966-1977. doi:10.1111/j.1476-5381.2011.01703.x [doi]

Stone, L. S., German, J. P., Kitto, K. F., Fairbanks, C. A., & Wilcox, G. L. (2014)., Morphine and clonidine combination therapy improves therapeutic window in mice: Synergy in antinociceptive but not in sedative or cardiovascular effects., PloS One, 9(10), e109903. doi:10.1371/journal.pone.0109903 [doi]

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Walentiny, D., Vann, R., Mahadevan, A., Kottani, R., Gujjar, R., & Wiley, J. (2013)., Novel 3-substituted rimonabant analogues lack delta(9) -tetrahydrocannabinol-like abuse-related behavioural effects in mice, British Journal of Pharmacology, 169(1), 10-20. doi:10.1111/bph.12099 [doi]

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Banevicius, M. A., Kaplan, N., Hafkin, B., & Nicolau, D. P. (2013)., Pharmacokinetics, pharmacodynamics and efficacy of novel FabI inhibitor AFN-1252 against MSSA and MRSA in the murine thigh infection model., Journal of Chemotherapy (Florence, Italy), 25(1), 26-31. doi:10.1179/1973947812Y.0000000061 [doi]

Jabes, D., Brunati, C., Candiani, G., Riva, S., Romano, G., Maffioli, S., . . . Donadio, S. (2014)., Pharmacological properties of NAI-603, a well-tolerated semisynthetic derivative of ramoplanin., Antimicrobial Agents and Chemotherapy, 58(4), 1922-1929. doi:10.1128/AAC.01620-13 [doi]

Carryn, S., Schaefer, D. A., Imboden, M., Homan, E. J., Bremel, R. D., & Riggs, M. W. (2012)., Phospholipases and cationic peptides inhibit cryptosporidium parvum sporozoite infectivity by parasiticidal and non-parasiticidal mechanisms., The Journal of Parasitology, 98(1), 199-204. doi:10.1645/GE-2822.1 [doi]

Inzalaco HN, Tepp WH, Fredrick C, Bradshaw M, Johnson EA, Pellett S., Posttranslational Regulation of Botulinum Neurotoxin Production in Clostridium botulinum Hall A-hyper, mSphere. 2021 Aug 25;6(4):e0032821. doi: 10.1128/mSphere.00328-21. Epub 2021 Aug 4.

Morbiato E, Bilel S, Tirri M, ArfĂ¨ R, Fantinati A, Savchuk S, Appolonova S, Frisoni P, Tagliaro F, Neri M, Grignolio S, Bertolucci C, Marti M., Potential of the zebrafish model for the forensic toxicology screening of NPS: A comparative study of the effects of APINAC and methiopropamine on the behavior of zebrafish larvae and mice, Neurotoxicology. 2020 May;78:36-46. doi: 10.1016/j.neuro.2020.02.003. Epub 2020 Feb 9.

Rayburn, E., Wang, W., Li, M., Zhang, X., Xu, H., Li, H., . . . Zhang, R. (2012), Preclinical pharmacology of novel indolecarboxamide ML-970, an investigative anticancer agent, Cancer Chemotherapy and Pharmacology, 69(6), 1423-1431. doi:10.1007/s00280-012-1851-9 [doi]

Zhou, X., Wang, J., Wu, J., Yang, X., Yung, B. C., Lee, L. J., & Lee, R. J. (2014), Preparation and evaluation of a novel liposomal formulation of cisplatin., European Journal of Pharmaceutical Sciences : Official Journal of the European Federation for Pharmaceutical Sciences, 66C, 90-95. doi:S0928-0987(14)00386-8 [pii]

Shakhov, A. N., Singh, V. K., Bone, F., Cheney, A., Kononov, Y., Krasnov, P., . . . Feinstein, E. (2012)., Prevention and mitigation of acute radiation syndrome in mice by synthetic lipopeptide agonists of toll-like receptor 2 (TLR2)., PloS One, 7(3), e33044. doi:10.1371/journal.pone.0033044 [doi]

Tiboni, G. M., & Ponzano, A. (2015)., Prevention of valproic acid-induced neural tube defects by sildenafil citrate, Reproductive Toxicology (Elmsford, N.Y.), 56, 175-179. doi:10.1016/j.reprotox.2015.03.004 [doi]

Mao, Y., Wang, J., Zhao, Y., Yan, R., Li, H., Chen, C. S., . . . Phelps, M. A. (2014), Quantification of OSU-2S, a novel derivative of FTY720, in mouse plasma by liquid chromatography-tandem mass spectrometry., Journal of Pharmaceutical and Biomedical Analysis, 98, 160-165. doi:10.1016/j.jpba.2014.05.022 [doi]

Copp, R. R., Peebles, D. D., Soref, C. M., & Fahl, W. E. (2013), Radioprotective efficacy and toxicity of a new family of aminothiol analogs, International Journal of Radiation Biology, 89(7), 485-492. doi:10.3109/09553002.2013.770579 [doi]

Izzotti, A., Balansky, R., D'Agostini, F., Longobardi, M., Cartiglia, C., La Maestra, S., . . . De Flora, S. (2013)., Relationships between pulmonary micro-RNA and proteome profiles, systemic cytogenetic damage and lung tumors in cigarette smoke-exposed mice treated with chemopreventive agents, Carcinogenesis, 34(10), 2322-2329. doi:10.1093/carcin/bgt178 [doi]

Gardner A, Tepp WH, Bradshaw M, Barbieri JT, Pellett S., Resolution of Two Steps in Botulinum Neurotoxin Serotype A1 Light Chain Localization to the Intracellular Plasma Membrane, Int J Mol Sci. 2021 Oct 15;22(20):11115. doi: 10.3390/ijms222011115.

Yang HS, Kim KM, Boonpraman N, Yoon SM, Seo JE, Park MW, Moon JS, Yoo SY, Yi SS., Respiratory Safety Evaluation in Mice and Inhibition of Adenoviral Amplification in Human Bronchial Endothelial Cells Using a Novel Type of Chlorine Dioxide Gas Reactor, Toxics. 2022 Jan 13;10(1):38. doi: 10.3390/toxics10010038.

Sekonyela, R., Palmer, J. M., Bok, J. W., Jain, S., Berthier, E., Forseth, R., . . . Keller, N. P. (2013), RsmA regulates aspergillus fumigatus gliotoxin cluster metabolites including cyclo(L-phe-L-ser), a potential new diagnostic marker for invasive aspergillosis., PloS One, 8(5), e62591. doi:10.1371/journal.pone.0062591 [doi]

Belcher, L. A., MacKenzie, S. A., Donner, M., Sykes, G. P., Frame, S. R., & Gillies, P. J. (2011)., Safety assessment of EPA-rich triglyceride oil produced from yeast: Genotoxicity and 28-day oral toxicity in rats., Regulatory Toxicology and Pharmacology : RTP, 59(1), 53-63. doi:10.1016/j.yrtph.2010.09.007 [doi]

Barr JT, Tran TB, Rock BM, Wahlstrom JL, Dahal UP., Strain-Dependent Variability of Early Discovery Small Molecule Pharmacokinetics in Mice: Does Strain Matter?, Drug Metab Dispos. 2020 Aug;48(8):613-621. doi: 10.1124/dmd.120.090621. Epub 2020 May 30.

Kendziorski, J. A., & Belcher, S. M. (2015)., Strain-specific induction of endometrial periglandular fibrosis in mice exposed during adulthood to the endocrine disrupting chemical bisphenol A, Reproductive Toxicology (Elmsford, N.Y.), 58, 119-130. doi:10.1016/j.reprotox.2015.08.001 [doi]

Wiley, J. L., Marusich, J. A., Zhang, Y., Fulp, A., Maitra, R., Thomas, B. F., & Mahadevan, A. (2012)., Structural analogs of pyrazole and sulfonamide cannabinoids: Effects on acute food intake in mice, European Journal of Pharmacology, 695(1-3), 62-70. doi:10.1016/j.ejphar.2012.08.019 [doi]

Tebben J, Zurhelle C, Tubaro A, Samdal IA, Krock B, Kilcoyne J, Sosa S, Trainer VL, Deeds JR, Tillmann U., Structure and toxicity of AZA-59, an azaspiracid shellfish poisoning toxin produced by Azadinium poporum (Dinophyceae)., Harmful Algae. 2023 May;124:102388. doi: 10.1016/j.hal.2023.102388. Epub 2023 Jan 22.

AlSharari, S. D., Carroll, F. I., McIntosh, J. M., & Damaj, M. I. (2012)., The antinociceptive effects of nicotinic partial agonists varenicline and sazetidine-A in murine acute and tonic pain models., The Journal of Pharmacology and Experimental Therapeutics, 342(3), 742-749. doi:10.1124/jpet.112.194506 [doi]

Chen, Z., He, Y., & Wang, Z. J. (2012), The beta-lactam antibiotic, ceftriaxone, inhibits the development of opioid-induced hyperalgesia in mice., Neuroscience Letters, 509(2), 69-71. doi:10.1016/j.neulet.2011.12.029 [doi]

Kinsey, S. G., Mahadevan, A., Zhao, B., Sun, H., Naidu, P. S., Razdan, R. K., . . . Lichtman, A. H. (2011)., The CB2 cannabinoid receptor-selective agonist O-3223 reduces pain and inflammation without apparent cannabinoid behavioral effects., Neuropharmacology, 60(2-3), 244-251. doi:10.1016/j.neuropharm.2010.09.004 [doi]

Kierstead, P. H., Okochi, H., Venditto, V. J., Chuong, T. C., Kivimae, S., Frechet, J. M. J., & Szoka, F. C. (2015)., The effect of polymer backbone chemistry on the induction of the accelerated blood clearance in polymer modified liposomes., Journal of Controlled Release : Official Journal of the Controlled Release Society, 213, 1-9. doi:S0168-3659(15)00630-6 [pii]

Brock, W. J., & Bell, T. A. (2012)., The in vitro and in vivo genotoxicity of benzocaine: A brief communication., International Journal of Toxicology, 31(3), 222-227. doi:10.1177/1091581812442230 [doi]

Boitano, S., Hoffman, J., Flynn, A. N., Asiedu, M. N., Tillu, D. V., Zhang, Z., . . . Price, T. J. (2015)., The novel PAR2 ligand C391 blocks multiple PAR2 signalling pathways in vitro and in vivo, British Journal of Pharmacology, doi:10.1111/bph.13238 [doi]

Hadad, N., & Levy, R. (2012)., The synergistic anti-inflammatory effects of lycopene, lutein, beta-carotene, and carnosic acid combinations via redox-based inhibition of NF-kappaB signaling., Free Radical Biology & Medicine, 53(7), 1381-1391. doi:10.1016/j.freeradbiomed.2012.07.078 [doi]

Wang M, Yang X, Pan Z, Wang Y, De La Cruz LK, Wang B, Tan C., Towards "CO in a pill": Pharmacokinetic studies of carbon monoxide prodrugs in mice, J Control Release. 2020 Nov 10;327:174-185. doi: 10.1016/j.jconrel.2020.07.040. Epub 2020 Aug 1.

D'Amico R, Gugliandolo E, Siracusa R, Cordaro M, Genovese T, Peritore AF, Crupi R, Interdonato L, Di Paola D, Cuzzocrea S, Fusco R, Impellizzeri D, Di Paola R., Toxic Exposure to Endocrine Disruptors Worsens Parkinson's Disease Progression through NRF2/HO-1 Alteration, Biomedicines. 2022 May 5;10(5):1073. doi: 10.3390/biomedicines10051073.

Protti-SĂĄnchez, Francesca; QuirĂłs-Guerrero, Luis; VĂĄsquez, VĂctor; Willink, Beatriz; Pacheco, Mariano; LeĂłn, Edwin; PrĂśhl, Heike; BolaĂąos, Federico;, Toxicity and Alkaloid Profiling of the Skin of the Golfo Dulcean Poison Frog Phyllobates vittatus (Dendrobatidae)., Journal of chemical ecology Vol.45, 2019

Protti-Sánchez, Francesca; Quirós-Guerrero, Luis; Vásquez, Víctor; Willink, Beatriz; Pacheco, Mariano; León, Edwin; Pröhl, Heike; Bolaños, Federico;, Toxicity and Alkaloid Profiling of the Skin of the Golfo Dulcean Poison Frog Phyllobates vittatus (Dendrobatidae)., Journal of chemical ecology Vol.45, 2019

Yang LY, Gao JL, Gao T, Dong P, Ma L, Jiang FL, Liu Y., Toxicity of polyhydroxylated fullerene to mitochondria, J Hazard Mater. 2016 Jan 15;301:119-26. doi: 10.1016/j.jhazmat.2015.08.046. Epub 2015 Aug 28.

Tait, S., Tassinari, R., Maranghi, F., & Mantovani, A. (2015)., Toxicogenomic analysis of placenta samples from mice exposed to different doses of BPA., Genomics Data, 4, 109-111. doi:10.1016/j.gdata.2015.04.004 [doi]

Yigit S, Hallaj NS, Sugarman JL, Chong LC, Roman SE, Abu-Taleb LM, Goodman RE, Johnson PE, Behrens AM., Toxicological assessment and food allergy of silk fibroin derived from Bombyx mori cocoons, Food Chem Toxicol. 2021 May;151:112117. doi: 10.1016/j.fct.2021.112117. Epub 2021 Mar 17.

Anand, S. S., Serex, T. L., Carpenter, C., Donner, E. M., Hoke, R., Buck, R. C., & Loveless, S. E. (2012)., Toxicological assessment of tridecafluorohexylethyl methacrylate (6:2 FTMAC)., Toxicology, 292(1), 42-52. doi:10.1016/j.tox.2011.11.016 [doi]

Karanewsky, D. S., Arthur, A. J., Liu, H., Chi, B., & Markison, S. (2015)., Toxicological evaluation of a novel cooling compound: 2-(4-methylphenoxy)-N-(1H-pyrazol-3-yl)-N-(2-thienylmethyl)acetamide., Toxicology Reports, 2, 1291-1309. doi:10.1016/j.toxrep.2015.09.001 [doi]

Kara, N. Z., Toker, L., Agam, G., Anderson, G. W., Belmaker, R. H., & Einat, H. (2013)., Trehalose induced antidepressant-like effects and autophagy enhancement in mice., Psychopharmacology, 229(2), 367-375. doi:10.1007/s00213-013-3119-4 [doi]

Vaccines

Bhaskar, V., Goldfine, I. D., Bedinger, D. H., Lau, A., Kuan, H. F., Gross, L. M., . . . Corbin, J. A. (2012), A fully human, allosteric monoclonal antibody that activates the insulin receptor and improves glycemic control., Diabetes, 61(5), 1263-1271. doi:10.2337/db11-1578 [doi]

Sia ZR, He X, Zhang A, Ang JC, Shao S, Seffouh A, Huang WC, D'Agostino MR, Teimouri Dereshgi A, Suryaprakash S, Ortega J, Andersen H, Miller MS, Davidson BA, Lovell JF., A liposome-displayed hemagglutinin vaccine platform protects mice and ferrets from heterologous influenza virus challenge, Proc Natl Acad Sci U S A. 2021 Jun 1;118(22):e2025759118. doi: 10.1073/pnas.2025759118.

Seitz, M., Beineke, A., Seele, J., Fulde, M., Valentin-Weigand, P., & Baums, C. G. (2012), A novel intranasal mouse model for mucosal colonization by streptococcus suis serotype 2., Journal of Medical Microbiology, 61(Pt 9), 1311-1318. doi:10.1099/jmm.0.043885-0 [doi]

Jedličková, Lucie; Dvo?ĂĄk, Jan; Hrachovinová, Ingrid; Ulrychová, Lenka; Kašný , Martin; Mikeš, Libor;, A novel Kunitz protein with proposed dual function from Eudiplozoon nipponicum (Monogenea) impairs haemostasis and action of complement in vitro, International journal for parasitology Vol.49, 2019

Jedličková, Lucie; Dvořák, Jan; Hrachovinová, Ingrid; Ulrychová, Lenka; Kašný , Martin; Mikeš, Libor;, A novel Kunitz protein with proposed dual function from Eudiplozoon nipponicum (Monogenea) impairs haemostasis and action of complement in vitro, International journal for parasitology Vol.49, 2019

He X, Zhou S, Huang WC, Seffouh A, Mabrouk MT, Morgan MT, Ortega J, Abrams SI, Lovell JF., A Potent Cancer Vaccine Adjuvant System for Particleization of Short, Synthetic CD8(+) T Cell Epitopes, ACS Nano. 2021 Mar 23;15(3):4357-4371. doi: 10.1021/acsnano.0c07680. Epub 2021 Feb 19.

Li, Yong; Duah, Ernest; Long, Nick; Persaud, Avinash; VanGundy, Zachary; Magliery, Thomas; Poi, Ming J;, An efficient and quantitative assay for epitope-tagged therapeutic protein development with a capillary western system., Bioanalysis Vol.11, 2019

Park, S., Gerber, S., & Lee, J. C. (2014), Antibodies to staphylococcus aureus serotype 8 capsular polysaccharide react with and protect against serotype 5 and 8 isolates., Infection and Immunity, 82(12), 5049-5055. doi:10.1128/IAI.02373-14 [doi]

Huang WC, Deng B, Seffouh A, Ortega J, Long CA, Suresh RV, He X, Miura K, Lee SM, Wu Y, Lovell JF., Antibody response of a particle-inducing, liposome vaccine adjuvant admixed with a Pfs230 fragment, NPJ Vaccines. 2020 Mar 18;5:23. doi: 10.1038/s41541-020-0173-x. eCollection 2020.

Pflepsen KR, Peterson CD, Kitto KF, Riedl MS, McIvor RS, Wilcox GL, Vulchanova L, Fairbanks CA., Biodistribution of Adeno-Associated Virus Serotype 5 Viral Vectors Following Intrathecal Injection, Mol Pharm. 2021 Oct 4;18(10):3741-3749. doi: 10.1021/acs.molpharmaceut.1c00252. Epub 2021 Aug 30.

Marshall, S., Hujer, A. M., Rojas, L. J., Papp-Wallace, K. M., Humphries, R. M., Spellberg, B., . . . Bonomo, R. A. (2017)., Can ceftazidime-avibactam and aztreonam overcome beta-lactam resistance conferred by metallo-beta-lactamases in enterobacteriaceae?, Antimicrobial Agents and Chemotherapy, 61(4), 10.1128/AAC.02243-16. Print 2017 Apr. doi:e02243-16 [pii]

Rangel G, Bárcena J, Moreno N, Mata CP, Castón JR, Alejo A, Blanco E., Chimeric RHDV Virus-Like Particles Displaying Foot-and-Mouth Disease Virus Epitopes Elicit Neutralizing Antibodies and Confer Partial Protection in Pigs, Vaccines (Basel). 2021 May 7;9(5):470. doi: 10.3390/vaccines9050470.

Velineni, S., Timoney, J. F., Russell, K., Hamlen, H. J., Pesavento, P., Fortney, W. D., & Crawford, P. C. (2014)., Clones of streptococcus zooepidemicus from outbreaks of hemorrhagic canine pneumonia and associated immune responses., Clinical and Vaccine Immunology : CVI, 21(9), 1246-1252. doi:10.1128/CVI.00222-14 [doi]

Vaickus, L. J., Bouchard, J., Kim, J., Natarajan, S., & Remick, D. G. (2012)., Cockroach allergens induce biphasic asthma-like pulmonary inflammation in outbred mice., The Journal of Asthma : Official Journal of the Association for the Care of Asthma, 49(5), 510-521. doi:10.3109/02770903.2012.678958 [doi]

Walton, K. D., Lord, A., Kendall, L. V., & Dow, S. W. (2014)., Comparison of 3 real-time, quantitative murine models of staphylococcal biofilm infection by using in vivo bioluminescent imaging., Comparative Medicine, 64(1), 25-33.

Henderson, A. J., Kumar, A., Barnett, B., Dow, S. W., & Ryan, E. P. (2012)., Consumption of rice bran increases mucosal immunoglobulin A concentrations and numbers of intestinal lactobacillus spp, Journal of Medicinal Food, 15(5), 469-475. doi:10.1089/jmf.2011.0213 [doi]

Burnley, B., & P Jones, H. (2017)., Corticotropin-releasing hormone improves survival in pneumococcal pneumonia by reducing pulmonary inflammation, Physiological Reports, 5(1), 10.14814/phy2.13000. doi:e13000 [pii]

Borrego, B., Rodriguez-Pulido, M., Mateos, F., de la Losa, N., Sobrino, F., & Saiz, M. (2013)., Delivery of synthetic RNA can enhance the immunogenicity of vaccines against foot-and-mouth disease virus (FMDV) in mice, Vaccine, 31(40), 4375-4381. doi:10.1016/j.vaccine.2013.07.008 [doi]

Beinborn, N. A., Du, J., Wiederhold, N. P., Smyth, H. D., & Williams, R. O.,3rd. (2012)., Dry powder insufflation of crystalline and amorphous voriconazole formulations produced by thin film freezing to mice., European Journal of Pharmaceutics and Biopharmaceutics : Official Journal of Arbeitsgemeinschaft Fur Pharmazeutische Verfahrenstechnik e.V, 81(3), 600-608. doi:10.1016/j.ejpb.2012.04.019 [doi]

Boilesen DR, Neckermann P, Willert T, Müller MD, Schrödel S, Pertl C, Thirion C, Asbach B, Wagner R, Holst PJ., Efficacy and synergy with cisplatin of an adenovirus vectored therapeutic E1E2E6E7 vaccine against HPV genome positive C3 cancers in mice, Cancer Immunol Res. 2022 Dec 19:CIR-22-0174. doi: 10.1158/2326-6066.CIR-22-0174. Online ahead of print.

Boilesen DR, Neckermann P, Willert T, MÃ¼ller MD, SchrÃ¶del S, Pertl C, Thirion C, Asbach B, Wagner R, Holst PJ., Efficacy and Synergy with Cisplatin of an Adenovirus Vectored Therapeutic E1E2E6E7 Vaccine against HPV Genome-Positive C3 Cancers in Mice., Cancer Immunol Res. 2023 Feb 3;11(2):261-275. doi: 10.1158/2326-6066.CIR-22-0174.

Bauza, K., Malinauskas, T., Pfander, C., Anar, B., Jones, E. Y., Billker, O., . . . Reyes-Sandoval, A. (2014)., Efficacy of a plasmodium vivax malaria vaccine using ChAd63 and modified vaccinia ankara expressing thrombospondin-related anonymous protein as assessed with transgenic plasmodium berghei parasites., Infection and Immunity, 82(3), 1277-1286. doi:10.1128/IAI.01187-13 [doi]

Spencer, A. J., Cottingham, M. G., Jenks, J. A., Longley, R. J., Capone, S., Colloca, S., . . . Hill, A. V. (2014)., Enhanced vaccine-induced CD8+ T cell responses to malaria antigen ME-TRAP by fusion to MHC class ii invariant chain, PloS One, 9(6), e100538. doi:10.1371/journal.pone.0100538 [doi]

Huang, C. T., Li, Z., Huang, Y., Zhang, G., Zhou, M., Chai, Q., . . . Fu, Z. F. (2014)., Enhancement of blood-brain barrier permeability is required for intravenously administered virus neutralizing antibodies to clear an established rabies virus infection from the brain and prevent the development of rabies in mice, Antiviral Research, 110, 132-141. doi:10.1016/j.antiviral.2014.07.013 [doi]

Kamali, A. N., Marin-Garcia, P., Azcarate, I. G., Puyet, A., Diez, A., & Bautista, J. M. (2015)., Experimental immunization based on plasmodium antigens isolated by antibody affinity., Journal of Immunology Research, 2015, 723946. doi:10.1155/2015/723946 [doi]

Chai, Q., She, R., Huang, Y., & Fu, Z. F. (2015)., Expression of neuronal CXCL10 induced by rabies virus infection initiates infiltration of inflammatory cells, production of chemokines and cytokines, and enhancement of blood-brain barrier permeability., Journal of Virology, 89(1), 870-876. doi:10.1128/JVI.02154-14 [doi]