ICR (CD-1^®) outbred mice

Uncover the versatility of ICR (CD-1^®) mice in biomedical research: ICR (CD-1^®) Mice: The Versatile Workhorses of Biomedical Research

Characteristics:

• Coat: Albino
• Docile disposition
• Excellent reproductive and maternal characteristics
• High incidence of retinal degeneration (Pde6b^rd1)
• Litter average: 11.5
• Most widely-used outbred mouse

Origin:

The Hsd:ICR (CD-1^®) mouse model is of Swiss origin and descended from the original two male and seven female albino non-inbred mice, imported by the Rockefeller Institute in 1926 from Lausanne, Switzerland. Descendants were distributed worldwide and the Ha/ICR was established in 1948 at the Institute of Cancer Research (ICR). A portion of the Ha/ICR colony was given to the Roswell Park Memorial Institute (RPMI). Charles River Laboratories (CRL) received their nucleus from RPMI in 1959, and caesarean rederived. Harlan obtained breeding stock from CRL in 1983. Harlan became Envigo in 2015, then Envigo was acquired by Inotiv in 2021.

Diet and Husbandry:

Inotiv’s iCare^TM Program focuses on creating industry awareness and continuing the highest-quality nutrition, bedding, and meaningful environmental enrichment for a wide range of laboratory animal species. Our iCare program supports the same standards of care we provide for our animal models while offering customers a convenient, single source for these essential products for their research facilities.

Diet:

 The ideal lab animal diet is the 2018 Teklad Global 18% Protein Rodent Diet (Irradiated or Autoclavable). 

Bedding:

The preferred bedding products are Teklad Diamond Soft or Ultra Soft Bedding.

Enrichment:

The environmental enrichment products that are provided in a rotation include Teklad Diamond Twists, as well as Sizzle-Nest, Shelters, Cocoons, and Paper Wool from our welfareplus+^® line of enrichment products.

Model Support Services:
Inotiv offers related model support services to deliver research-ready models to your facility:

• Surgical Services
• Preconditioning Services
• Aging Services
• Contract Breeding Services
• Biospecimen Services

Health Monitoring Report Update
Inotiv is standardizing global health monitoring to deliver consistent, rigorous surveillance. Updated reports featuring our revised testing frequencies and agents will begin with the September 2026 cycle with reports becoming available between mid-September and early October.

Historical data for the previous 18 months will remain available under the Technical Resources tab. For details on monitored agents and testing frequencies, visit our Health Monitoring Reports page.  Please contact us if you have any questions or concerns.

• United States - 208A - Frederick, MD
• United States - 237 - Livermore, CA

Available regions:

Order code: 030 - US

• iCare Program: Continuity of Care — US
• Hematology and Clinical Chemistry — Female ICR (CD-1®) Outbred Mice
• Hematology and Clinical Chemistry — Male ICR (CD-1®) Outbred Mice
• Model Information Sheet — US
• Model Information Sheet — EU
• Fighting mice data sheet

Archived Health Monitoring Reports

• United States - 208A - Frederick, MD
• United States - 237 - Livermore, CA
• United Kingdom (Hillcrest) - Building 16
• The Netherlands - Barrier 2