Exploratory Toxicology

In Vivo Pharmacokinetics (PK) and Acute Tolerability studies are critical components of any drug discovery program. Exploratory Toxicology data can contribute to more informed decision making when addressing the safety of a drug even when projects are in the drug discovery phase.

Without Exploratory Toxicology in the drug discovery phase, important safety considerations that could arise later in development may impact overall success. This can result in significant financial losses and setbacks in the drug development process.

At Inotiv, we recognize the importance of Exploratory Toxicology and how it is essential to work with a trusted partner to ensure that your drug candidates are being assessed appropriately. Inotiv offers a comprehensive suite of toxicology services to support drug discovery and development. Through scientific partnership with our clients, our team of experts work diligently to provide high-quality data and insights to ensure the safety and efficacy of new drug candidates.

At Inotiv, we provide integrated solutions for telemetry, encompassing mice, rats, guinea pigs, canines and non-human primates.

Learn how efficiently your drug discovery program needs can be met by utilizing Inotiv’s expertise, including:

• In Vivo Pharmacokinetics in multiple species
• Rapid PK Screening Studies with quick data turn around
• Definitive PK studies to enable understanding of clearance mechanisms and metabolism
• Acute Tolerability Assessment to understand dose proportionality and acute toxicity
• Exposure analysis by LC-MS/MS and PK/TK modeling included for a bundled solution