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129 inbred mice

Strain:

129S2/SvHsd

Produced in:

U.K.

Research use:

Ovary transplant and ova transfer studies, Production of targeted mutations due to the availability of several lines of embryonic stem cells

5Ht3a-Cre knockin rats

Produced in:

U.S. Cryopreserved

Research use:

Cre Tool for conditional expression or deletion in 5HT3a+ neurons, Expression/knockout of floxed genes, Neuroscience, Optogenetics

A inbred mice

Strain:

A/JOlaHsd

Produced in:

U.S., U.K., The Netherlands

Research use:

Behavior, Carcinogenesis, General studies, Teratogenesis

ACI inbred rats

Strain:

ACI/SegHsd

Produced in:

U.S. Cryopreserved

Research use:

Carcinogenesis, Estrogen-induced pituitary growth, Transplant immunology

AHR knockout rats

Produced in:

U.S. Cryopreserved

Research use:

ADMET, Obesity, Cholestasis, Cytochrome p450 pathways, Drug metabolism, Hepatotoxicity, Xenobiotic

Alpha-Synuclein A53T SNCA knockin rats

Produced in:

U.S.

Research use:

Dopaminergic cell toxicity, Neuroscience, Parkinson's disease

Alpha-Synuclein-SNCA knockout rats

Produced in:

U.S.

Research use:

Neuroscience, Dopaminergic cell toxicity, Neuroscience, Parkinson's disease

ApoE knockout rats

Produced in:

U.S.

Research use:

Atherosclerosis, Cardiovascular, General studies, Neuroscience, Alzheimer's disease, Cardiovascular, Neurodegenerative diseases

App knockout rats

Produced in:

U.S. Cryopreserved

Research use:

Alzheimer's disease, Dementia, Memory loss, Neurodegeneration, Neuroscience, Synaptic formation and repair

Athymic nude mice

Produced in:

U.S., U.K., The Netherlands

Research use:

Autoimmune disease, Gene therapy, General studies, Imaging, Immunology, Oncology, Surgical, Transplantation, Tumor Cell Growth, Tumor growth, Sentinel model - Heterozygous Hsd:Athymic Nude-Foxn1nu/Foxn1+

Athymic nude rats

Produced in:

U.S., The Netherlands

Research use:

General studies, Immunology, Oncology, Transplantation, Sentinel model – Heterozygous Hsd:RH-Foxn1rnu/Foxn1+

B-NDG B2m double knockout plus mice

Produced in:

U.S., U.K., The Netherlands

Research use:

General studies, Oncology, Humanization applications, Graft vs. host disease research, Drug efficacy evaluation

B-NDG hIL15 mice

Produced in:

U.S., The Netherlands

Research use:

Immunotherapy, Oncology research, Infectious disease, Humanization applications, NK cell role in tumorigenesis, Antibody drug efficacy evaluation

B-NDG knockout mice

Produced in:

U.S., The Netherlands

Research use:

Aging, Chemoresistance, General studies, Immunotherapy, Oncology, Stem cells, Tumor Cell Growth, Tumor growth, Humanization applications, Infectious disease

B6C3F1 hybrid mice

Produced in:

U.S., The Netherlands

Research use:

General studies, Toxicology, Carcinogenicity, Embryo donors, Toxicology

B6CBAF1 hybrid mice

Strain:

B6CBAF1/OlaHsd

Produced in:

The Netherlands

B6D2F1 hybrid mice

Produced in:

U.S., The Netherlands

Research use:

Behavior, Bioassay of nutrients, drugs, and hormones, Tumorigenicity

BALB/c inbred mice

Produced in:

U.S., U.K., The Netherlands

Research use:

Aging, Antibody production, Cardiovascular, COVID-19, General studies, Infectious disease, Monoclonal antibodies, Oncology, Pharmacology, Teratology, Toxicology, Transplantation, General purpose

BALB/c inbred mice
Biosecure Plus™

Produced in:

U.S., U.K. Biosecure Plus™

Research use:

Aging, Antibody production, Cardiovascular, COVID-19, General studies, Infectious disease, Monoclonal antibodies, Oncology, Pharmacology, Teratology, Toxicology, Transplantation, General purpose

BALB/c nude mice

Produced in:

U.K., The Netherlands

Research use:

Imaging, Immunology, Oncology, Transplantation, Tumor growth, Antibody production, Autoimmune disease, Sentinel model - Heterozygous BALB/cOlaHsd-Foxn1nu/Foxn1+

Bcrp knockout rats

Produced in:

U.S.

Research use:

ADMET, Tissue distribution, DMPK efflux assay, Drug-drug interactions, Drug metabolism, Drug transporter, Efficacy assay, Formulation blood brain barrier efflux, Neuroscience, Tissue distribution

BDNF knockout rats

Produced in:

U.S. Cryopreserved

Research use:

ADMET, Metabolism, Neuroscience, Alzheimer's disease, Depression, Huntington's disease, Memory loss, Nerve growth and development, Neuroscience, Pain, Post-traumatic stress disorder, Schizophrenia

Brown Norway inbred rats

Strain:

BN/RijHsd

Produced in:

U.S., U.K.

Research use:

Aging, General studies, Oncology, Transplantation, Allergic Respiratory Disease, Leukemia, Nephrology

BSEP knockout rats

Produced in:

U.S. Cryopreserved

Research use:

ADMET, Cholestasis, Drug-drug interactions, Drug-induced cholestasis (DIC), Drug metabolism, Drug transporter

C3H inbred mice

Strain:

C3H/HeNHsd

Produced in:

U.S., The Netherlands

Research use:

General studies, Immunology, Ocular disease

C57BL/6 aged inbred mice

Produced in:

The Netherlands

Research use:

Age-associated pathology, Cardiovascular, Immune response, Longevity, Memory, Metabolism, Motor skills, Osteoarthritis, Neoplasia, Neurobiology, Renal degeneration, Reproductive senescence, Vision and hearing

C57BL/6 albino mice

Produced in:

U.S., U.K., The Netherlands

Research use:

Ovarian transfer, Source of albino C57BL/6 embryos for chimera generation

C57BL/6 inbred mice

Produced in:

U.S., U.K., The Netherlands

Research use:

Aging, Alcoholism, Alpha Synuclein, Background for Genetically Engineered Mouse Models, Behavior, Behavioral and learning disabilities, Cardiovascular, COVID-19, Diabetes type 2, Diet induced obesity, Drug Addiction, General studies, Genetically modified, Immunology, Infectious disease, Neuroscience, Oncology, Osteoporosis, Surgical, Toxicology, Vaccines, Background for induced and genetically-modified models, Behavior and learning disabilities, Diet-induced obesity, Drug addiction, Superovulation

C57BL/6 inbred mice
Biosecure Plus™

Produced in:

U.S., U.K. Biosecure Plus™

Research use:

Aging, Alcoholism, Alpha Synuclein, Behavior, Behavioral and learning disabilities, Cardiovascular, COVID-19, Diabetes type 2, Diet induced obesity, General studies, Genetically modified, Immunology, Infectious disease, Neuroscience, Oncology, Osteoporosis, Surgical, Toxicology, Vaccines, Background for induced and genetically-modified models, Behavior and learning disabilities, Diet-induced obesity, Drug addiction, Superovulation

C57BL/Ka inbred mice

Produced in:

The Netherlands

Cacna1c knockout rats

Produced in:

U.S. Cryopreserved

Research use:

Cardiovascular, Neurodegeneration, Neuropathology, Neuroscience, Social behavior, Alzheimer's disease, Autism (ASD), Dementia, Memory loss, Synaptic formation and repair

CamKIIa-Cre knockin rats

Produced in:

U.S. Cryopreserved

Research use:

Cre Tool for conditional expression or deletion in CamKIIa+ neurons, Expression/knockout of floxed genes, Neuroscience, Optogenetics

CAR knockout rats

Produced in:

U.S. Cryopreserved

Research use:

ADMET, Cytochrome p450 pathways, Cholestasis, Hepatotoxicity, Drug metabolism, Xenobiotic

CB6F1 hybrid mice

Produced in:

U.S., The Netherlands

Research use:

Behavior, Immunology, Infection, Reproductive Biology

CBA inbred mice

Strain:

CBA/JCrHsd

Produced in:

U.S.

Research use:

General studies, Immunology, Only approved mouse strain for use in the Local Lymph Node Assay, a refined alternative research method for evaluating the allergic contact dermatitis potential of chemicals and compounds

CBA/Ca inbred mice

Strain:

CBA/CaOlaHsd

Produced in:

U.K., The Netherlands

Research use:

General studies, Hearing

CD2F1 hybrid mice

Strain:

CD2F1/Hsd

Produced in:

U.S.

Research use:

Carcinogenesis, Pharmacology

CFTR knockout rats

Produced in:

U.S. Cryopreserved

Research use:

Lung Disease, Chloride transport, Cystic Fibrosis, Lung Disease, Thiocyanide transport

CHD8 knockout rats

Produced in:

U.S. Cryopreserved

Research use:

Autism (ASD), Neuroscience

Chrna7 knockout rats

Produced in:

U.S. Cryopreserved

Research use:

Epilepsy, Neuronal growth and transport studies, Neuroscience, Schizophrenia

Cntnap2 knockout rats

Produced in:

U.S. Cryopreserved

Research use:

Autism, Neuroscience, Cell adhesion, Language disorders, Synaptic Plasticity

Cotton rats

Strain:

Hsd:Cotton Rat

Produced in:

U.S.

Research use:

Infectious disease, Measles, Parainfluenza Type 3, Adenoviral vector-based gene therap, Herpes Simplex, Human metapneumovirus, Monkeypox, Mycobacterium tuberculosis, Polio, COVID-19

Cox1 knockout rats

Produced in:

U.S. Cryopreserved

Research use:

Asthma, Colitis, Crohn's disease, Immunology, Multiple sclerosis, Platelet defects/Platelet aggregation, Renal dysplasia, Rheumatoid arthritis, Inflammation/Autoimmune disorders, Thrombosis/Cardiac fibrosis, Vascular defects

Cox2 knockout rats

Produced in:

U.S. Cryopreserved

Research use:

Asthma, Colitis, Crohn's disease, Immunology, Inflammation/Autoimmune disorders, Multiple sclerosis, Platelet defects/Platelet aggregation, Renal dysplasia, Rheumatoid arthritis, Thrombosis/Cardiac fibrosis, Vascular defects

Cynomolgus macaques

Strain:

M. fascicularis

Produced in:

U.S.

Research use:

Cellular therapies, COVID-19, Diabetes, General studies, Immunology, Infectious disease, Neuroscience, Obesity, Pharmacology, Toxicology

DA (Dark Agouti) inbred rats

Strain:

DA/OlaHsd

Produced in:

U.S., U.K.

Research use:

Cardiovascular Experimental allergic encephalomyelitis, Induced rheumatoid arthritis, Oncology, Transplantation

Dahl Salt-Sensitive/Resistant (Rapp) inbred rats

Strain:

SR/JrHsd, SS/JrHsd

Produced in:

U.S. Cryopreserved

Research use:

Heart failure, Nephropathy, Salt-sensitive hypertension, Stroke

DBA/1 inbred mice

Strain:

DBA/1OlaHsd

Produced in:

U.S., U.K., The Netherlands

Research use:

Adjuvant-induced arthritis, Immunology, Inflammation

DBA/2 inbred mice

Produced in:

U.S., U.K., The Netherlands

Research use:

Audiogenic seizures, Progressive hearing loss

Diabetic (db/db) mice

Produced in:

U.S., The Netherlands

Research use:

General studies, Immunology, Obesity, Immunodeficiency, Peripheral neuropathy

Disc1 knockout rats

Produced in:

U.S. Cryopreserved

Research use:

Neuroscience, Bipolar disorder, Neuronal growth and transport studies, Schizophrenia

Dopamine Transporter DAT-Cre knockin rats

Produced in:

U.S. Cryopreserved

Research use:

Neuroscience, Cre Tool for conditional expression or deletion in dopaminergic neurons, DREDD, Expression/knockout of floxed genes, Optogenetics

Dopamine Transporter DAT-Cre knockin rats

Produced in:

U.S. Cryopreserved

Research use:

Neuroscience, Cre Tool for conditional expression or deletion in dopaminergic neurons, DREDD, Expression/knockout of floxed genes, Optogenetics

Dunkin Hartley guinea pigs

Strain:

HsdDhl:DH

Produced in:

The Netherlands

Research use:

Cardiovascular, General studies, Ocular studies, Pharmacology, Toxicology, Auditory Studies

Dutch belted rabbits

Strain:

HsdHaz:(DB) SPF

Produced in:

U.S.

Research use:

General studies, Immunology, Neuroscience, Pharmacology, Teratology, Toxicology

Faah knockout rats

Produced in:

U.S. Cryopreserved

Research use:

Analgesia, Cannabinoids, Neuroscience, Nociception, Pain

Fischer 344 aged inbred rats

Strain:

F344/NHsd Aged

Produced in:

U.S.

Research use:

Aging, Allergic encephalomyelitis, Autoimmune disease, Carcinogenicity, General studies, Oncology, Ophthalmology, Toxicology, Age-associated pathology, Cardiovascular, Immune response, Longevity, Memory, Metabolism, Motor skills, Neoplasia, Neurobiology, Osteoarthritis, Renal degeneration, Reproductive senescence, Vision and hearing

Fischer 344 inbred rats

Strain:

F344/NHsd

Produced in:

U.S.

Research use:

Aging, Allergic encephalomyelitis, Autoimmune disease, Carcinogenicity, General studies, Infectious disease, Oncology, Ophthalmology, Surgical, Toxicology

Fmr1 knockout rats

Produced in:

U.S.

Research use:

Autism, Fragile x syndrome, Neuroscience, Autism (ASD), Fragile X syndrome, Neuroscience

FVB inbred mice

Produced in:

U.S., U.K., The Netherlands

Research use:

Transgenic model development

Gabrb3 knockout rats

Produced in:

U.S. Cryopreserved

Research use:

Autism (ASD), Epilepsy, Neuroscience, Prader-Willi syndrome

Golden Syrian hamsters

Strain:

HsdHan®:AURA

Produced in:

U.S.

Research use:

Behavior, Carcinogenicity, COVID-19, Infectious disease, Metabolism, Oncology, Surgical, Toxicology, Hibernation, Hypercholesterolemia, Syrian Hamster Embryo (SHE) Cell Transformation Assay

hApoE2 knockin rats

Produced in:

U.S. Cryopreserved

Research use:

Atherosclerosis, Cardiovascular, Alzheimer's disease, Dopaminergic cell toxicity, Neuroscience

hApoE3 knockin rats

Produced in:

U.S.

Research use:

Atherosclerosis, Cardiovascular, Alzheimer's disease, Dopaminergic cell toxicity, Neuroscience

hApoE4 knockin rats

Produced in:

U.S.

Research use:

Alzheimer's disease, Cardiovascular, Neuroscience, Neurodegenerative diseases

Holtzman® outbred rats

Produced in:

U.S.

Research use:

General studies, Neurology, Oncology, Reproduction, Teratology, Toxicology

Humanized ACE2 (hACE2) knockin mice

Produced in:

U.S.

Research use:

Cardiovascular, Infectious disease, COVID-19

Humanized ACE2 (hACE2) knockin rats

Produced in:

U.S.

Research use:

Cardiovascular, Infectious disease, COVID-19

Humanized ACE2/Tmprss2 (hACE2/hTmprss2) double knockin mice

Produced in:

U.S.

Research use:

Infectious disease, COVID-19

Humanized Tmprss2 (hTmprss2) knockin mice

Produced in:

U.S.

Research use:

Oncology, Infectious disease, COVID-19

ICR (CD-1®) outbred mice

Produced in:

U.S., U.K., The Netherlands

Research use:

Aging, COVID-19, General studies, Infectious disease, Oncology, Teratology, Toxicology, Vaccines

Ldlr knockout rats

Produced in:

U.S. Cryopreserved

Research use:

Cardiovascular, Artery disease, Atherogenesis, Atherosclerosis- Cholesterol transportation, Hypertension, Insulin resistant, Lipoprotein, Metabolism (Triglyceride - Cholesterol), Obesity, Type II diabetes

Leptin knockout rats

Produced in:

U.S. Cryopreserved

Research use:

Cardiovascular, Artery disease, Atherogenesis, Atherosclerosis, Diabetes, HypertensionInsulin resistance, Lipoprotein/Cholesterol transportation, Metabolism (Triglyceride/Cholesterol), Obesity, Type II diabetes

Lewis inbred rats

Strain:

LEW/SsNHsd

Produced in:

U.S.

Research use:

Adjuvant-induced arthritis, Experimental allergic encephalomyelitis, General studies, Immunology, Oncology, Preclinical (PK/PD), Surgical, Transplantation, Adjuvant-induced arthritis

Lgals1 (Gal1) knockout rats

Produced in:

U.S. Cryopreserved

Research use:

Asthma, Colitis, Crohn's disease, Immunology, Inflammation/Autoimmune disorders, Multiple sclerosis, Oncology, Platelet defects/Platelet aggregation, Renal dysplasia, Rheumatoid arthritis, Thrombosis/Cardiac fibrosis, Vascular defects

Lister Hooded outbred rats

Strain:

HsdOla:LH

Produced in:

U.K., The Netherlands

Research use:

Behavior

Long Evans (Blue Spruce) outbred rats

Strain:

HsdBlu:LE

Produced in:

U.S.

Research use:

Aging, Behavior, Diet induced obesity, Diet/Obesity, General studies, Metabolism, Nutrition

Lrrk1 knockout rats

Produced in:

U.S. Cryopreserved

Research use:

Neuronal apoptosis, Neuroscience, Parkinson's disease

Lrrk1-Lrrk2 knockout rats

Produced in:

U.S. Cryopreserved

Research use:

Neuronal apoptosis, Neuroscience, Parkinson's disease

Lrrk2 knockout rats

Produced in:

U.S. Cryopreserved

Research use:

Neuroscience, Parkinson's disease, Neuronal apoptosis

Mdr1a knockout rats

Produced in:

U.S.

Research use:

ADMET, Pharmacology, Blood brain barrier efflux, DMPK assay, Drug metabolism, Drug resistance, Drug transporter, Efficacy, Formulation drug-drug interactions, Neurotoxicology, PK-PD efflux assay

Mdr1a-1b knockout rats

Produced in:

U.S.

Research use:

Drug-drug interactions, ADMET, Blood brain barrier efflux, DMPK assay, Drug metabolism, Drug resistance, Drug transporter, Efficacy, Formulation drug-drug interactions, Neurotoxicology, PK-PD efflux assay

Mdr1a-Bcrp knockout rats

Produced in:

U.S.

Research use:

ADMET, Blood brain barrier efflux, DMPK assay, Drug metabolism, Drug resistance, Drug transporter, Efficacy, Formulation drug-drug interactions, Neurotoxicology, PK-PD efflux assay

MeCP2 knockout rats

Produced in:

U.S. Cryopreserved

Research use:

Neuroscience, Rett syndrome, Autism (ASD), Cognition, Neuroscience, Rett Syndrome

Met knockout rats

Produced in:

U.S. Cryopreserved

Research use:

Autism (ASD), Autoimmune disorders, Neuroscience, Synaptic Plasticity

mGluR5 knockout rats

Produced in:

U.S. Cryopreserved

Research use:

Neuroscience, Anxiety, Autism (ASD), Cognition, Fragile X syndrome, Pain, Schizophrenia

Mrp1 knockout rats

Produced in:

U.S. Cryopreserved

Research use:

ADMET, Drug metabolism, Drug resistance, Drug transporter, Studying excretion pathways in cancer

Mrp2 knockout rats

Produced in:

U.S. Cryopreserved

Research use:

ADMET, Tissue distribution, DMPKPK/PDFormulation, Drug transporter, Dubin-Johnson syndrome, Efficacy Drug-drug interactions, Efflux assays, Tissue distribution

ND4 Swiss Webster outbred mice

Strain:

Hsd:ND4

Produced in:

U.S.

Research use:

General studies, Infectious disease, Reproductive, Retinal ischemia research, Pain and neuroscience, Toxicology

Neurexin1-Nrxn1 knockout rats

Produced in:

U.S. Cryopreserved

Research use:

Autism, Neuroscience, Schizophrenia, Synaptic Plasticity

Neuroligin 3 (Nlgn3) knockout rats

Produced in:

U.S. Cryopreserved

Research use:

Neuroscience, Asperger's syndrome, Autism (ASD), Synaptic Plasticity

New Zealand white rabbits

Produced in:

U.S., U.K.

Research use:

Antibody production, Atherosclerosis, Behavioral and learning disabilities, Biomedical research, Cardiovascular, Dermatology, General studies, Immunology, Oncology, Ophthalmology, Osteology, Pharmacology, Surgical, Teratology, Toxicology, Dermatology, Renal Studies

NIH inbred mice

Strain:

NIH/OlaHsd

Produced in:

U.K.

Research use:

General purpose studies

NIH Swiss outbred mice

Strain:

Hsd:NIHS

Produced in:

U.S., U.K.

Research use:

General studies

NMRI nude mice

Produced in:

The Netherlands

Research use:

Oncology, Tumor growth, Antibody production, Autoimmune disease, Immunology, Transplantation

NMRI outbred mice

Strain:

HsdWin:NMRI

Produced in:

The Netherlands

Research use:

General studies, Immunology, Transplantation

NOD.SCID mice

Produced in:

U.S., The Netherlands

Research use:

General studies, Immunology, Oncology, Transplantation, Tumor Cell Growth, Tumor growth

Non-Swiss albino outbred mice

Strain:

Hsd:NSA(CF-1®)

Produced in:

U.S.

Research use:

General studies, Surgical, Infectious disease, Toxicology

Oat1 knockout rats

Produced in:

U.S. Cryopreserved

Research use:

ADMET, Drug-drug interactions, Drug metabolism, Drug transporter, Hepatotoxicity

Oat3 knockout rats

Produced in:

U.S. Cryopreserved

Research use:

ADMET, Drug-drug interactions, Drug metabolism, Drug transporter, Hepatotoxicity

Oct1 knockout rats

Produced in:

U.S. Cryopreserved

Research use:

ADMET, Drug-drug interactions, Drug metabolism, Drug transporter, Hepatotoxicity

Oct2 knockout rats

Produced in:

U.S. Cryopreserved

Research use:

Drug transporter, ADMET, Drug-drug interactions, Drug metabolism, Hepatotoxicity

Oprm1 knockout rats

Produced in:

U.S. Cryopreserved

Research use:

Addiction, Analgesia, Neuroscience, Nociception, Pain

p53 knockout rats

Produced in:

U.S. Cryopreserved

Research use:

Autoimmune disease, Cancer, Hematopoiesis, Infectious disease, Oncology, Vaccine development, Xenografts

p75NTR knockout rats

Produced in:

U.S. Cryopreserved

Research use:

Neuroscience, Analgesia, Neuronal apoptosis, Nociception, Pain

Park2 Parkin knockout rats

Produced in:

U.S.

Research use:

Metabolism, Neuroscience, Parkinson's disease, Dopaminergic cell toxicity

Park7 DJ-1 knockout rats

Produced in:

U.S. Cryopreserved

Research use:

Neuroscience, Parkinson's disease, Dopaminergic cell toxicity

Parvalbumin-Cre knockin rats

Produced in:

U.S.

Research use:

Neuroscience, Cre Tool for conditional expression or deletion in PV+ neurons, Expression/knockout of floxed genes, Neuroscience, Optogenetics

Pink1 knockout rats (Park6)

Produced in:

U.S.

Research use:

Neuroscience, Parkinson's disease, Stress-induced neurological dysfunction

Pink1/Parkin double knockout rats (Park6/Parkin)

Produced in:

U.S.

Research use:

Neuroscience, Parkinson's disease, Stress-induced neurological dysfunction

Ppara knockout rats

Produced in:

U.S. Cryopreserved

Research use:

ADMET, Autoimmune disorders, Cell proliferation, Drug metabolism, Diabetes, Immunology, Inflammation, Lipid metabolism, Obesity, Wound healing, Xenobiotic

Prkdc knockout rats

Produced in:

U.S. Cryopreserved

Research use:

Immunology, Cancer metastasis, Oncology, Tumor cell growth, Xenograft

Pten knockout rats

Produced in:

U.S. Cryopreserved

Research use:

Autism, Neuroscience, Cancer, Neuroscience, Oncology

PXR knockout rats

Produced in:

U.S. Cryopreserved

Research use:

ADMET, Cholestasis, Cytochrome p450 pathways, Drug metabolism, Hepatotoxicity, Xenobiotic

PXR-CAR knockout rats

Produced in:

U.S. Cryopreserved

Research use:

ADMET, Cholestasis, Cytochrome p450 pathways, Drug metabolism, Hepatotoxicity, Xenobiotic

PXR/CAR/AHR knockout rats

Produced in:

U.S. Cryopreserved

Research use:

ADMET, Cholestasis, Cytochrome p450 pathways, Drug metabolism, Hepatotoxicity, Xenobiotic

Rag1 knockout rats (Fischer 344)

Produced in:

U.S. Cryopreserved

Research use:

Cancer metastasis, Immunology, Inflammation/Autoimmune disorders, Oncology, Thrombosis/Cardiac fibrosis, Vaccine development, Xenograft

Rag1 knockout rats (Sprague Dawley)

Produced in:

U.S. Cryopreserved

Research use:

Oncology, Cancer metastasis, Hematopoieses, Immunology, Inflammation/Autoimmune disorders, Infectious disease, Thrombosis/Cardiac fibrosis, Vaccine development, Vascular defects, Xenograft

Rag2 knockout rats (Fischer 344)

Produced in:

U.S. Cryopreserved

Research use:

Cancer metastasis, Inflammation/Autoimmune disorders, Thrombosis/Cardiac fibrosis, Vaccine development, Vascular defects, Xenograft

Rag2 knockout rats (Sprague Dawley)

Produced in:

U.S.

Research use:

Infectious disease, Oncology, Vaccines, Cancer metastasis, Immunology, Inflammation/Autoimmune disorders, Hematopoieses, Thrombosis/Cardiac fibrosis, Vascular defects, Xenograft

Rag2-Il2rg double knockout mice (R2G2®)

Produced in:

U.S., U.K., The Netherlands

Research use:

Imaging, Immunology, Immunotherapy, Neuropathology, Oncology, Stem cells, Tumor biology, Tumor growth, Cancer cell transplantation, Infectious disease

Rbfox1 knockout rats

Produced in:

U.S. Cryopreserved

Research use:

Autism (ASD), Neurodegenerative Disorders, Neuroscience

Rhesus macaques

Strain:

M. mulatta

Produced in:

U.S.

Research use:

COVID-19, Diabetes, General studies, Immunology, Infectious disease, Neuroscience, Obesity, Pharmacology, Toxicology, Transplantation

SAM (senescence accelerated mice) inbred mice

Produced in:

The Netherlands

Research use:

Accelerated senescence studies, Age-dependent disorders, Brain atrophy, Deficits in learning and memory, Emotional disorders Aging process, Geriatric pathogenesis, Hearing impairment, Hyperinflation of the lungs, Senile amyloidosis (apolipoprotein A-II), Senile osteoporosis

SCID mice

Produced in:

U.S., U.K., The Netherlands, France

Research use:

General studies, Imaging, Immunology, Oncology, Transplantation, Tumor Cell Growth, Tumor growth

SCID/beige mice

Produced in:

U.S., The Netherlands

Research use:

Gene therapy, General studies, Immunology, Oncology, Transplantation, Tumor Cell Growth, Tumor growth, Teratology

SHrN® hairless NOD.SCID mice

Produced in:

Italy Cryopreserved

Research use:

Oncology, Humanization applications, Imaging applications, Xenograft transplantation

SJL inbred mice

Strain:

SJL/JCrHsd

Produced in:

U.S.

Research use:

Behavior, Immunology

Spontaneously hypertensive inbred rats

Strain:

SHR/NHsd

Produced in:

U.S.

Research use:

Hypertension, Surgical, Insulin resistant

Sprague Dawley® aged outbred rats

Produced in:

U.S.

Research use:

Age-associated pathology, Cardiovascular, Immune response, Longevity, Memory, Metabolism, Motor skills, Neoplasia, Neurobiology, Osteoarthritis, Renal degeneration, Reproductive senescence, Vision and hearing

Sprague Dawley® outbred rats

Produced in:

U.S., U.K., The Netherlands

Research use:

Aging, Cardiovascular, COVID-19, Diabetes induced obesity, Diet induced obesity, General studies, Immunology, Infectious disease, Metabolism, Neurology, Neuroscience, Nutrition, Oncology, Preclinical (PK/PD), Reproductive, Surgical, Teratology, Toxicology, Tumor biology

Sst-Cre knockin rats

Produced in:

U.S. Cryopreserved

Research use:

Cre Tool for conditional expression or deletion in SST+ neurons, Expression/knockout of floxed genes, Neuroscience, Optogenetics

Tbx21 (T-beta) knockout rats

Produced in:

U.S. Cryopreserved

Research use:

Asthma, Colitis, Crohn's disease, Immunology, Inflammation/Autoimmune disorders, Multiple sclerosis, Oncology, Platelet defects/Platelet aggregation, Renal dysplasia, Rheumatoid arthritis, Thrombosis/Cardiac fibrosis, Vascular defects

tdTomato reporter knockin rats

Produced in:

U.S.

Research use:

Neuroscience, Tomato fluorescence, Expression of td, Optogenetics, Tomato fluorescence when Cre-recombinase is introduced

TO outbred mice

Strain:

HsdOla:TO

Produced in:

U.K.

Research use:

General purpose

Tph2-Cre knockin rats

Produced in:

U.S. Cryopreserved

Research use:

Parkinson's disease, Cre Tool for conditional expression or deletion in Tph2+ neurons, Expression/knockout of floxed genes, Neuroscience, Optogenetics

Trpv1 knockout rats

Produced in:

U.S. Cryopreserved

Research use:

Neuroscience, Analgesia, Cannabinoids, Nociception, Pain, Thermoregulation

Tyrosine Hydroxylase TH-Cre knockin rats

Produced in:

U.S.

Research use:

Neuroscience, Cre Tool for conditional expression or deletion in Th+ neurons, DREADD, Expression/knockout of floxed genes, Optogenetics

Vgat-Cre knockin rats

Produced in:

U.S. Cryopreserved

Research use:

Cre Tool for conditional expression or deletion in VGAT+ neurons, Expression/knockout of floxed genes, Neuroscience, Optogenetics

VIP-Cre knockin rats

Produced in:

U.S. Cryopreserved

Research use:

Neuroscience, Cre Tool for conditional expression or deletion in VIP+ neurons, Expression/knockout of floxed genes, Neuroscience, Optogenetics

Wistar Furth inbred rats

Strain:

WF/NHsd

Produced in:

U.S. Cryopreserved

Research use:

Oncology, Immunology, Leukemia, Transplantation

Wistar Han® outbred rats

Strain:

RccHan®:WIST

Produced in:

U.S., U.K., The Netherlands

Research use:

Aging, General studies, Nutrition, Oncology, Preclinical (PK/PD), Surgical, Teratology, Toxicology

Wistar Kyoto inbred rats

Strain:

WKY/NHsd

Produced in:

U.S., U.K.

Research use:

Immunology, Inbred, normotensive control for SHR rat

Wistar outbred rats

Strain:

Hsd:WI

Produced in:

U.S.

Research use:

General studies, Aging, Nutrition, Oncology, Teratology

Wistar Unilever outbred rats

Strain:

HsdCpb:WU

Produced in:

U.K.

Research use:

Aging, General purpose model, Nutrition, Oncology, Teratology

Zucker obese rats

Produced in:

U.S.

Research use:

Cardiovascular, Diabetes type 2, General studies, Obesity, Surgical

SCIENCE Surgeon - clinical@2x-

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