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Drug Discovery Consulting: A Drug Discovery Consultative Approach

Drug discovery and development present a challenging landscape, but you don't have to navigate it alone. As your partner, we provide a consultative approach that leverages our years of expertise and scientific excellence to deliver personalized insights that illuminate your path. Our collaborative approach expedites your journey, proactively minimizing potential risks and maximizing your chances of success.

Discovery-Program-Infographic

Why Partner with Inotiv for Consultative Discovery?

Inotiv goes beyond the simple drug discovery consulting. We offer a consultative partnership, leveraging our deep industry experience, scientific leadership, and attentive, decisive advice to uncover key insights into your target pathway. We design, run, and interpret study results that identify potential risks for your drug candidate, empowering you to make informed decisions before significant investment.

As a true extension of your team, you’ll benefit from:

  • Tailored Consultative Solutions: We don't just provide services; we engage in a consultative process to understand your team's goals and needs. Together, we craft a preclinical discovery and development program that precisely aligns with your objectives.
  • Early Consultative Insights: Our exploratory preclinical safety evaluations aren't just tests; they're consultative analyses that reveal critical dose-exposure relationships and potential adverse effects, enabling swift, informed decision-making.
  • Dedicated Consultative Partnership: Inotiv's commitment to scientific continuity means you'll work with a dedicated team of experts who provide ongoing consultative guidance and support throughout your compound's development journey.

Understanding Your Discovery Program

1
Business Model & Program Goals
TELL US ABOUT YOUR PROGRAM STRATEGY
 
  • Disease Indication
  • Competitive Landscape
  • Target Product Profile
  • Therapeutic Modality
  • Key Milestones
  • Develop, Partner, or Sell
2
Is Target Validated or Novel
TELL US ABOUT YOUR TARGET
 
  • In Vitro Pharmacology/Target Engagement
  • Expression in Target Tissue
  • Genetically Engineered Model
  • Proof of Pharmacology & Mechanism
3
Therapeutic Approach
LEAD OPTIMIZATION (SMALL MOLECULE OR BIOTHERAPEUTIC)

 

  • Active Chemistry
  • Mechanism of Action
  • Potency & Selectivity
  • DMPK Optimization
  • PK-PD and PK Prediction
4
Model Selection & Translation
DISEASE EFFICACY PLAN
 
  • Animal Model(s) Characterization
  • Disease/Target Biomarker Plan
  • Disease Pathways Analysis (Proteomics)
  • Quantitative Pathology
5
Safety Assessment Strategy
SAFETY & TOLERABILITY
 
  • Species Selection
  • Formulation
  • Dose Proportionality & Sex Differences
  • TK Modeling
  • Margin of Safety
  • Mechanistic Toxicology

 

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