Established in 1925 by Robert Dawley, the original Sprague Dawley rat colony was obtained by Harlan in 1980 through the acquisition of Sprague-Dawley, Inc. Harlan became Envigo in 2015, then Envigo was acquired by Inotiv in 2021. The Hsd:Sprague Dawley® SD® rat has a wide array of historical research use including in the field of cardiology. In order to provide historical and reference data for the research community, several of these articles are outlined below.
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