Less than 21 day studies
Historical control data on histological findings in shorter than 21 day studies in RccHan®:WIST Rats
Compiled data from 80 studies
Historical control data on histological findings in shorter than 21 day studies in RccHan®:WIST Rats
(Recovery)
Compiled data from 80 studies
28 day studies
Historical control data on histological findings in RccHan®:WIST rats
(Planned sacrifices after 28-days, recovery)
Compiled data from 104 studies
Appendix: Statistics
Historical control data on histological findings in RccHan®:WIST Rats
Compiled data from 340 studies
Historical Control Data on histological findings in RccHan®:WIST Rats (Recovery)
Compiled data from 340 studies
13 week studies
Historical control data on histological fndings in RccHan®:WIST
(Planned sacrifices after 13 weeks, recovery)
Compiled data from 80 studies
Appendix: Statistics
Historical control data on histological findings in RccHan®:WIST
(Planned sacrifices after 13 weeks)
Compiled data from 80 studies
Appendix: Statistics
Historical control data on histological findings in RccHan®:WIST (recovery)
Compiled data from 132 studies
26 week studies
Historical control data on non-neoplastic findings in RccHan®:WIST
(Planned sacrifices after 26 weeks, recovery)
Compiled data from 9 studies
Appendix: Statistics
Historical control data on histological findings in RccHan®:WIST rats
(Planned sacrifices after 26 weeks)
Compiled data from 7 studies
Appendix: Statistics
103 week studies
Historical control data on non-neoplastic findings in RccHan®:WIST rats from 2-year bioassays
(Planned sacrifices prior to 103 weeks)
Compiled data from 50 studies
Appendix: Statistics
Historical control data on non-neoplastic findings in RccHan®:WIST from 2-year bioassays
(Planned sacrifice after 103 weeks)
Compiled data from 50 studies
Appendix: Statistics
Historical control data on neoplastic findings in RccHan®:WIST from 2 years bioassays
(Planned sacrifice prior to 103 weeks)
Compiled data from 50 studies
Appendix: Statistics
Historical control data on neoplastic findings in RccHan®:WIST rats from 2-year bioassays
(Planned sacrifice after 103 weeks)
Compiled data from 50 studies
Appendix: Statistic
Prenatal studies
Historical control data from prenatal developmental toxicity studies performed during 2002 to 2006
Compiled data from 36 studies
Historical control data on reproduction /developmental toxicity studies in RccHan®:WIST, Wistar Hannover rats
Compiled data from 6 studies
Appendix: Statistics
28 day 1st generation studies
Historical control data on reprotoxicicity 1- generation - studies in RccHan®:WIST rats
(Planned sacrifice after 28-days)
Compiled data from 10 studies
Historical control data from pre- and postnatal developmental toxicity studies
Compiled data from 4 studies
Historical control data on postnatal indices and sperm analysis in P- and F1- generation
Compiled data from 8 studies
Sperm analysis
Historical control data of sperm analyses from 2-generation and fertility studies
Compiled data from 4 studies
2nd generation studies
Historical control data on reprotoxicity 2- generation toxicity - studies in RccHan®:WIST, Wistar Hannover rat
Compiled data from 7 studies
Comprehensive overview of the RccHan®:WIST global model
Food and water consumption
Historical control data of body weights, food consumption and water consumption
Compiled data from multiple studies
Clinical signs
Historical control data of clinical symptoms in RccHan®:WIST, Wistar Hannover rats
Compiled data from over 4000 animals
Clinical chemistry
Historical control data of clinical biochemistry in RccHan®:WIST, Wistar Hannover rats
Compiled data from over 1900 animals
Historical control data of clinical biochemistry in RccHan®:WIST, Wistar Hannover rats
Compiled data from over 200 studies
Hematology
Historical control data of hematological data in RccHan®:WIST, Wistar Hannover rats
Compiled data from over 200 studies
Organ weights
Historical data - OECD 416 Studies - P Generation Males / Females- Organ Weights
Compiled data from 7 studies
Historical control data of absolute and relative organ weights
Compiled data from over 700 studies
Historical control data of absolute organ weights in reprotoxicology
Compiled data from multiple studies
Urinalysis
A 104-week historical control oncogenicity study with interim necropsies in RccHan®:WIST rats
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