Inotiv
CLOSE ×

Inotiv's mouse and rat revitalization services offer a crucial solution for laboratories facing challenges with their valuable mouse and rat colonies. Over time, factors like genetic drift, pathogen contamination, or poor breeding performance can compromise the integrity of your animal models. Our comprehensive revitalization program utilizes advanced techniques, including embryo rederivation and in vitro fertilization (IVF), to eliminate unwanted variables and restore the health and genetic fidelity of your colonies. We produce specific pathogen-free (SPF) rodents, ensuring the reliability and reproducibility of your in vivo research. By entrusting your mouse revitalization or rat revitalization to Inotiv, you safeguard your research investments, maintain genetic consistency, and optimize your animal model management for peak performance.

When you utilize our revitalization service, you can expect:

  • Comprehensive Rodent Revitalization: We offer embryo or sperm revitalization utilizing your preferred breeders combined with genetic testing to ensure the preservation of your valuable animal model genetics.
  • Rigorous Health Monitoring: Our health status evaluation employs customer-approved health monitoring profiles on recipient females and offspring, guaranteeing specific pathogen-free (SPF) rodent models to meet your facility needs.
  • Pathogen Elimination: Through our meticulous process, we ensure the complete elimination of pathogenic and opportunistic microorganisms, safeguarding the integrity of your in vivo studies.
  • Unrestricted Animal Model Distribution: Revitalization eliminates distribution restrictions, enabling seamless collaboration with investigators and facilitating international animal model transfer.
  • Reduced Research Variability: Our services minimize variables that can affect research results, ensuring genetic consistency and enhancing the reliability of your rodent models.
  • Flexible Offspring Delivery: We offer flexible options, including direct delivery of offspring to your facility or colony expansion services at Inotiv, streamlining your animal model management.

NOTE: Embryos produced from in vitro fertilization will be transferred into recipient animals to produce the rederived offspring.

Order today

+1 800 793 7287

Online order  

Rederivation services offered:

Service Requirements Project outcome

Revitalization of embryos with health screening - Mouse and Rat

  • 100 cryopreserved embryos
  • Freezing and thawing protocol
  • QC report
  • Small cohort with specified health status
  • Includes rederivation services, recipient and offspring housing and health monitoring.

Revitalization of sperm with health screening - Mouse only

  • 3-5 straws of cryopreserved sperm
  • Freezing and thawing protocol
  • QC report
  • Small cohort with specified health status
  • Includes rederivation services, recipient and offspring housing and health monitoring.

Revitalization of sperm with health screening (from cryopreserved embryos of a discontinued mouse line)

Minimum of forty (40) cryopreserved embryos

  • Small cohort with specified health status
  • Includes rederivation services, recipient and offspring housing and health monitoring.

*Once completed, your line can remain at Inotiv for colony maintenance and breeding or get shipped back to your facility. Your project manager will work with you to customize a plan that best suits your objectives.

Please download our contract breeding and support services brochure  indicating different options.

For more information on our services and to request a quote on your next project, please fill out our breeding questionnaire or contact us in North America at servicesPMG.US@inotiv.com or in Europe at servicesPMG.EU@inotiv.com.

SCIENCE Surgeon - clinical@2x-

Scientific Insights

Keep up-to-date with the latest industry thinking and scientific insights

Explore Today Explore Today  
Group of businesspeople working over digital tablet and laptop in the office

Speak to an Expert

Contact Our Specialist Today

Contact Us Contact Us  

Subscribe to updates from Inotiv

Sign up and you’ll receive the latest updates that matter to you, delivered straight to your inbox.

Subscribe now