C57BL/6 aged inbred mice: C57BL/6JRccHsd Aged

select features

Coat: Black
Haplotype: H-2^b
High preference for alcohol
Incidence of hydrocephalous
Low tumor incidence
Microphthalmia
Most widely-used inbred strain
The C57BL/6JRccHsd subline does not carry the Nnt (nicotinamide nucleotice transhydrogenase) gene deletion

Common age-associated conditions include:

Hair loss
Loss of motor skills and sensory perception
Presence of spontaneous tumors
Reduced immunologic and physiologic function
Loss of vision, e.g. retinal degeneration, development of cataracts

Origin:

The C57BL/JRccHsd mice originate from Jackson Laboratory, Bar Harbor, Maine and were moved in 1973 to RCC Ltd. (formerly Ibm and BRL) in Füllinsdorf, Switzerland. To Harlan Laboratories through acquisition in 2004. Harlan became Envigo in 2015, then Envigo was acquired by Inotiv in 2021.

The Netherlands - Barrier 1

Available regions:

Asia-Pacific Austria Baltic states Belgium East Europe France Germany Ireland Italy Portugal Scandinavia Spain Switzerland The Netherlands United States United Kingdom Other regions

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