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Discovery Pathology

Short summary here

Inotiv
  • Six board-certified veterinary pathologists
  • Experience in wide range of discovery models, systems expertise
  • Non-GLP study support
    • Model development and characterization, phenotyping
    • Drug/compound efficacy, established or custom/flexible scoring systems
    • Discovery toxicology, early safety/tolerability, biodistribution
    • Pathology consultation
      • Client-facing, highly communicative and collaborative
      • Model selection and development, study design, endpoint feasibility and analysis
      • Evaluation of complex endpoints and specialized histology methods/tissue types
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Spatial biology and biomarker analysis

  • Evaluation of protein and transcriptional expression, pathology at a biomarker level
  • Architectural and phenotypic image analysis, custom and AI-driven algorithms
  • Qualification and quantification of molecular targets in relation to disease phenotypes
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Spatial transcriptomics

  • Spatially-resolved tissue gene expression
  • Transcriptomic diversity combining whole-slide imaging to visualize and quantify biomarker expression across tissue landscape
  • Visualization of transcriptional activity, regulatory and biomarker networks, disease signatures, transcriptional characterization of disease or efficacy
  • 10X Genomics Visium V2 and HD, 10X Genomics Xenium platforms
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