tdTomato reporter knockin rats

• Background strain: Long Evans Hooded

Availability: Live colony
Zygosity genotype: Homozygous

This model possesses the fluorophore tdTomato, sitting behind a floxed stop codon in the Rosa26 locus under control of the CAG promoter. By introducing Cre-recombinase through viral transduction or crossing with one of our Cre-driver rats, tdTomato fluorescence will be observed anywhere Cre- is expressed. The tdTomato Reporter rat is useful for applications requiring tissue specific expression, including optogenetics and breeding with Cre-driver lines.

Origin:

The tdTomato Reporter KI rat model was originally created at SAGE Labs, Inc. in St. Louis, MO and distributed out of the Boyertown, PA facility. The line continues to be maintained through the original SAGE Labs animal inventory acquired by Envigo, then Envigo was acquired by Inotiv in 2021.

Diet and Husbandry:
Our rodent models are raised and maintained on Teklad diet, bedding, and enrichment products:

• Diet: Teklad Global Rodent Diet
• Bedding: Teklad Contact Bedding (U.S. only)
• Enrichment: Teklad Enrichment Products (U.S. only)

Model Support Services:
Inotiv offers related model support services to deliver research-ready models to your facility:

• Surgical Services
• Preconditioning Services
• Aging Services
• Contract Breeding Services
• Biospecimen Services

Health Monitoring Report Update
Inotiv is standardizing global health monitoring to deliver consistent, rigorous surveillance. Updated reports featuring our revised testing frequencies and agents will begin with the September 2026 cycle with reports becoming available between mid-September and early October.

Historical data for the previous 18 months will remain available under the Technical Resources tab. For details on monitored agents and testing frequencies, visit our Health Monitoring Reports page.  Please contact us if you have any questions or concerns.

• United States - Building 410 - Denver, PA

Available regions:

For pricing information, please contact us using the phone number above.

• Model information sheet