Sprague Dawley^® aged outbred rats

• Coat: Albino
• Hair Loss
• Loss of motor skills and sensory perception
• Loss of vision, e.g. retinal degeneration, development of cataracts
• Presence of spontaneous tumors
• Reduced immunologic and physiologic function

Origin:

Established in 1925 by Robert Dawley, the original Sprague Dawley rat colony was obtained by Harlan in 1980 through the acquisition of Sprague-Dawley, Inc. Harlan became Envigo in 2015, then Envigo was acquired by Inotiv in 2021. The Hsd:Sprague Dawley^® SD^® rat has a wide array of historical research use including in the field of cardiology. In order to provide historical and reference data for the research community, several of these articles are outlined below.

Diet and Husbandry:

Inotiv’s iCare^TM Program focuses on creating industry awareness and continuing the highest-quality nutrition, bedding, and meaningful environmental enrichment for a wide range of laboratory animal species. Our iCare program supports the same standards of care we provide for our animal models while offering customers a convenient, single source for these essential products for their research facilities.

Diet:

The ideal lab animal diet is the 2018 Teklad Global 18% Protein Rodent Diet (Irradiated or Autoclavable).

Bedding:

The preferred bedding products are Teklad Diamond Soft or Ultra Soft Bedding.

Enrichment:

The environmental enrichment products that are provided in a rotation include Teklad Diamond Twists, as well as Sizzle-Nest, Shelters, Cocoons, and Paper Wool from our welfareplus+^® line of enrichment products.

Model Support Services:
Inotiv offers related model support services to deliver research-ready models to your facility:

• Surgical Services
• Preconditioning Services
• Aging Services
• Contract Breeding Services
• Biospecimen Services

Health Monitoring Report Update
Inotiv is standardizing global health monitoring to deliver consistent, rigorous surveillance. Updated reports featuring our revised testing frequencies and agents will begin with the September 2026 cycle with reports becoming available between mid-September and early October.

Historical data for the previous 18 months will remain available under the Technical Resources tab. For details on monitored agents and testing frequencies, visit our Health Monitoring Reports page.  Please contact us if you have any questions or concerns.

• United States - 208A - Frederick, MD

Available regions:

Order code: 002 - ES

• iCare Program: Continuity of Care — US

Archived Health Monitoring Reports

• United States - 208A - Frederick, MD