Downstream Antibody Services

Immunogenicity immunization

Inotiv Bioproducts provides a unique immunogenicity immunization service in a variety of species, such as rats, mice, guinea pigs, and rabbits. We provide serum samples from a wide range of antigens, bacteria, viruses, lipids, nucleic acids and other proteins. Non-immunogenic haptens require conjugation with an epitope such as a protein or polysaccharide before they can illicit an immunologic response. Standard protocols are available for each species, or we can follow your specific protocol. All our procedures and production records are fully documented, allowing complete traceability.

Service	Antigen	Production type	Production capacity	Area of use	Advantages
Immunogenicity immunization	Proteins, viruses, variety of antigen	Rabbits, mice rats, guinea pigs	Small to large scale (all size runs available)	Vaccine, research discovery	Variety of speciesUSDA licensed Standard/custom protocols

Antibody purification

Inotiv Bioproducts can purify mg-to-gram quantities of your monoclonal or polyclonal antibodies utilizing a wide array of protein purification methods, for research or cGMP diagnostic use. We can also purify any raw antibodies that have been produced in your lab or from another supplier. Our scientific staff will work with you to discuss the best options available to meet your needs. Our goal is to develop a procedure which provides the best balance between yield, purity and cost.

Service	Antigen	Production type	Production capacity	Area of use	Advantages
Antibody purification IEF, SEC, MW testing Fab & F(ab’)2 fragmentation FITC, Biotin, Alk Phos, and HRP conjugation	Monoclonals Polyclonals Secreted proteins IgM IgY	Protein A & G, Antigen affinity, Hydrophobic interaction, Size exclusion, Ammonium sulfate, Ion exchange	Small to large scale (20mg - 20g scale available)	Diagnostics, cGMP diagnostic research	Variety of methodsLow endotoxin for in vivo usecGMP compliant for diagnostic usePurify client’s in-house antibodyStandard/custom protocols

Mouse antibody production (MAP) testing
If your Custom Antibody Production project must be free of mycoplasma or viral contamination, we recommend our mouse antibody production (MAP), rat antibody production (RAP) and hamster antibody production (HAP) testing programs. These tests will screen your cell lines against the adventitious viruses associated with your cell line’s origin. Testing is available by both PCR and serology.

Downstream processing (processing and cell line services)
We have expanded our cell line and processing capabilities to offer a wider selection of services, thus helping you to complete your research more efficiently.

Bioburden
Endotoxin
Sterility
Subcloning

Cell banking
Cell line stability
Mycoplasma cleanup
Viability

Cell weaning
Cell recovery
Cell line isotyping
IgG testing

Our technical staff has extensive experience in microbiology, virology, cell biology, pathology, and lab animal medicine. This translates into knowing that your projects will be dealt with in a professional and timely manner.

Customer experiences

When you work with Inotiv, you can be confident that through our experience, we ensure consistent and reliable products for research and industry.

Discover how Inotiv helps companies in providing custom antibody services, click here to read more.

Get in touch — Contact our antibodies and bioproducts team

At Inotiv, we are dedicated to helping you secure the potential of your product by providing you with a comprehensive selection of research animals. Our experts are ready to assist you.

If you have a more general inquiry click here to get in touch — general inquiry form.

North America
- Tel: +1 800 972 4362
- Bioproducts / antibodies: bioproducts.na@inotiv.com
Asia, Europe and other countries
- Tel: +44 (0)1869 243 241
- Antibodies: antibodies.eu@inotiv.com
- Bioproducts: biologicals.eu@inotiv.com