Strain:

HsdSage:LE-5HT3a^{em1(T2A-Cre)Sage}

Produced in:

U.S. Cryopreserved

Research use:

Cre Tool for conditional expression or deletion in 5HT3a+ neurons, Expression/knockout of floxed genes, Neuroscience, Optogenetics

Strain:

HsdSage:SD-Ahr^em1Sage

Produced in:

U.S. Cryopreserved

Research use:

ADMET, Obesity, Cholestasis, Cytochrome p450 pathways, Drug metabolism, Hepatotoxicity, Xenobiotic

Strain:

HsdSage:SD-SNCA^{em1(SNCA-A53T)Sage}

Produced in:

U.S.

Research use:

Dopaminergic cell toxicity, Neuroscience, Parkinson's disease

Strain:

HsdSage:SD-SNCA^em1Sage

Produced in:

U.S.

Research use:

Neuroscience, Dopaminergic cell toxicity, Neuroscience, Parkinson's disease

Strain:

HsdSage:SD-ApoE^em1Sage

Produced in:

U.S.

Research use:

Atherosclerosis, Cardiovascular, General studies, Neuroscience, Alzheimer's disease, Cardiovascular, Neurodegenerative diseases

Strain:

HsdSage:SD-App^em1Sage

Produced in:

U.S. Cryopreserved

Research use:

Alzheimer's disease, Dementia, Memory loss, Neurodegeneration, Neuroscience, Synaptic formation and repair

Strain:

HsdSage:SD-Abcg2^em1Sage

Produced in:

U.S.

Research use:

ADMET, Tissue distribution, DMPK efflux assay, Drug-drug interactions, Drug metabolism, Drug transporter, Efficacy assay, Formulation blood brain barrier efflux, Neuroscience, Tissue distribution

Strain:

HsdSage:SD-Bdnf^em1Sage

Produced in:

U.S. Cryopreserved

Research use:

ADMET, Metabolism, Neuroscience, Alzheimer's disease, Depression, Huntington's disease, Memory loss, Nerve growth and development, Neuroscience, Pain, Post-traumatic stress disorder, Schizophrenia

Strain:

HsdSage:SD-Abcb11^em1Sage

Produced in:

U.S. Cryopreserved

Research use:

ADMET, Cholestasis, Drug-drug interactions, Drug-induced cholestasis (DIC), Drug metabolism, Drug transporter

Strain:

HsdSage:SD-Cacna1c^em1Sage

Produced in:

U.S. Cryopreserved

Research use:

Cardiovascular, Neurodegeneration, Neuropathology, Neuroscience, Social behavior, Alzheimer's disease, Autism (ASD), Dementia, Memory loss, Synaptic formation and repair

Strain:

HsdSage:LE-CAMKIIA^{em1(IRES-Cre)Sage}

Produced in:

U.S. Cryopreserved

Research use:

Cre Tool for conditional expression or deletion in CamKIIa+ neurons, Expression/knockout of floxed genes, Neuroscience, Optogenetics

Strain:

HsdSage:SD-NR1I3^em1Sage

Produced in:

U.S. Cryopreserved

Research use:

ADMET, Cytochrome p450 pathways, Cholestasis, Hepatotoxicity, Drug metabolism, Xenobiotic

Strain:

HsdSage:SD-Cftr^em1Sage

Produced in:

U.S. Cryopreserved

Research use:

Lung Disease, Chloride transport, Cystic Fibrosis, Lung Disease, Thiocyanide transport

Strain:

HsdSage:SD-CHD8^em1Sage

Produced in:

U.S. Cryopreserved

Research use:

Autism (ASD), Neuroscience

Strain:

HsdSage:SD-Chrna7^em1Sage

Produced in:

U.S. Cryopreserved

Research use:

Epilepsy, Neuronal growth and transport studies, Neuroscience, Schizophrenia

Strain:

HsdSage:SD-Cntnap2^em1Sage

Produced in:

U.S. Cryopreserved

Research use:

Autism, Neuroscience, Cell adhesion, Language disorders, Synaptic Plasticity

Strain:

HsdSage:SD-Cox1^em1Sage

Produced in:

U.S. Cryopreserved

Research use:

Asthma, Colitis, Crohn's disease, Immunology, Multiple sclerosis, Platelet defects/Platelet aggregation, Renal dysplasia, Rheumatoid arthritis, Inflammation/Autoimmune disorders, Thrombosis/Cardiac fibrosis, Vascular defects

Strain:

HsdSage:SD-Cox2^em1Sage

Produced in:

U.S. Cryopreserved

Research use:

Asthma, Colitis, Crohn's disease, Immunology, Inflammation/Autoimmune disorders, Multiple sclerosis, Platelet defects/Platelet aggregation, Renal dysplasia, Rheumatoid arthritis, Thrombosis/Cardiac fibrosis, Vascular defects

Strain:

HsdSage:SD-Disc1^em1Sage

Produced in:

U.S. Cryopreserved

Research use:

Neuroscience, Bipolar disorder, Neuronal growth and transport studies, Schizophrenia

Strain:

HsdSage:SD-Slc6a3^{em1(Dat-cre)Sage}

Produced in:

U.S. Cryopreserved

Research use:

Neuroscience, Cre Tool for conditional expression or deletion in dopaminergic neurons, DREDD, Expression/knockout of floxed genes, Optogenetics

Strain:

HsdSage: LE-Slc6a3^{em1(Dat-cre)Sage}

Produced in:

U.S. Cryopreserved

Research use:

Neuroscience, Cre Tool for conditional expression or deletion in dopaminergic neurons, DREDD, Expression/knockout of floxed genes, Optogenetics

Strain:

HsdSage:SD-Faah^em1Sage

Produced in:

U.S. Cryopreserved

Research use:

Analgesia, Cannabinoids, Neuroscience, Nociception, Pain

Strain:

HsdSage: SD-Fmr1-/null^em1Sage, HsdSage:SD-Fmr1+/-^em1Sage, HsdSage:SD-Fmr1^em1Sage

Produced in:

U.S.

Research use:

Autism, Fragile x syndrome, Neuroscience, Autism (ASD), Fragile X syndrome, Neuroscience

Strain:

HsdSage:SD-Gabrb3^em1Sage

Produced in:

U.S. Cryopreserved

Research use:

Autism (ASD), Epilepsy, Neuroscience, Prader-Willi syndrome

Strain:

HsdSage:SD-ApoE2^{em1(hApoE2)Sage}

Produced in:

U.S. Cryopreserved

Research use:

Atherosclerosis, Cardiovascular, Alzheimer's disease, Dopaminergic cell toxicity, Neuroscience

Strain:

HsdSage:SD-ApoE3^{em1(hApoE3)Sage}

Produced in:

U.S.

Research use:

Atherosclerosis, Cardiovascular, Alzheimer's disease, Dopaminergic cell toxicity, Neuroscience

Strain:

HsdSage:SD-ApoE4^{em1(hApoE4)Sage}

Produced in:

U.S.

Research use:

Alzheimer's disease, Cardiovascular, Neuroscience, Neurodegenerative diseases

Strain:

Hsd:SD-Ace2^em1(ACE2)Env

Produced in:

U.S.

Research use:

Cardiovascular, Infectious disease, COVID-19

Strain:

HsdSage:SD-Ldlr^em1Sage

Produced in:

U.S. Cryopreserved

Research use:

Cardiovascular, Artery disease, Atherogenesis, Atherosclerosis- Cholesterol transportation, Hypertension, Insulin resistant, Lipoprotein, Metabolism (Triglyceride - Cholesterol), Obesity, Type II diabetes

Strain:

HsdSage:SD-Lep^em1Sage

Produced in:

U.S. Cryopreserved

Research use:

Cardiovascular, Artery disease, Atherogenesis, Atherosclerosis, Diabetes, HypertensionInsulin resistance, Lipoprotein/Cholesterol transportation, Metabolism (Triglyceride/Cholesterol), Obesity, Type II diabetes

Strain:

HsdSage:SD-Lgals1^em1Sage

Produced in:

U.S. Cryopreserved

Research use:

Asthma, Colitis, Crohn's disease, Immunology, Inflammation/Autoimmune disorders, Multiple sclerosis, Oncology, Platelet defects/Platelet aggregation, Renal dysplasia, Rheumatoid arthritis, Thrombosis/Cardiac fibrosis, Vascular defects

Strain:

HsdSage:LE-Lrrk1^em1Sage

Produced in:

U.S. Cryopreserved

Research use:

Neuronal apoptosis, Neuroscience, Parkinson's disease

Strain:

HsdSage:LE-Lrrk1/Lrrk2^em1Sage

Produced in:

U.S. Cryopreserved

Research use:

Neuronal apoptosis, Neuroscience, Parkinson's disease

Strain:

HsdSage:LE-Lrrk^em1Sage

Produced in:

U.S. Cryopreserved

Research use:

Neuroscience, Parkinson's disease, Neuronal apoptosis

Strain:

HsdSage:SD-Mdr1a^em1Sage

Produced in:

U.S.

Research use:

ADMET, Pharmacology, Blood brain barrier efflux, DMPK assay, Drug metabolism, Drug resistance, Drug transporter, Efficacy, Formulation drug-drug interactions, Neurotoxicology, PK-PD efflux assay

Strain:

HsdSage:SD-Mdr1a^em1SageMdr1b^em1Sage

Produced in:

U.S.

Research use:

Drug-drug interactions, ADMET, Blood brain barrier efflux, DMPK assay, Drug metabolism, Drug resistance, Drug transporter, Efficacy, Formulation drug-drug interactions, Neurotoxicology, PK-PD efflux assay

Strain:

HsdSage:SD-Mdr1a^em1SageAbcg2^em1Sage

Produced in:

U.S.

Research use:

ADMET, Blood brain barrier efflux, DMPK assay, Drug metabolism, Drug resistance, Drug transporter, Efficacy, Formulation drug-drug interactions, Neurotoxicology, PK-PD efflux assay

Strain:

HsdSage:SD-Mecp2^em1Sage

Produced in:

U.S. Cryopreserved

Research use:

Neuroscience, Rett syndrome, Autism (ASD), Cognition, Neuroscience, Rett Syndrome

Strain:

HsdSage:SD-Met^em1Sage

Produced in:

U.S. Cryopreserved

Research use:

Autism (ASD), Autoimmune disorders, Neuroscience, Synaptic Plasticity

Strain:

HsdSage:SD-Grm5^em1Sage

Produced in:

U.S. Cryopreserved

Research use:

Neuroscience, Anxiety, Autism (ASD), Cognition, Fragile X syndrome, Pain, Schizophrenia

Strain:

HsdSage:SD-Abcc1a^em1Sage

Produced in:

U.S. Cryopreserved

Research use:

ADMET, Drug metabolism, Drug resistance, Drug transporter, Studying excretion pathways in cancer

Strain:

HsdSage:SD-Abcc2^em1Sage

Produced in:

U.S. Cryopreserved

Research use:

ADMET, Tissue distribution, DMPKPK/PDFormulation, Drug transporter, Dubin-Johnson syndrome, Efficacy Drug-drug interactions, Efflux assays, Tissue distribution

Strain:

HsdSage:SD-Nrxn1^em1Sage

Produced in:

U.S. Cryopreserved

Research use:

Autism, Neuroscience, Schizophrenia, Synaptic Plasticity

Strain:

HsdSage:SD-Nlgn3^em1Sage

Produced in:

U.S. Cryopreserved

Research use:

Neuroscience, Asperger's syndrome, Autism (ASD), Synaptic Plasticity

Strain:

HsdSage:SD-Slc22a6^em1Sage

Produced in:

U.S. Cryopreserved

Research use:

ADMET, Drug-drug interactions, Drug metabolism, Drug transporter, Hepatotoxicity

Strain:

HsdSage:SD-Slc22a8^em1Sage

Produced in:

U.S. Cryopreserved

Research use:

ADMET, Drug-drug interactions, Drug metabolism, Drug transporter, Hepatotoxicity

Strain:

HsdSage:SD-Slc22a1^em1Sage

Produced in:

U.S. Cryopreserved

Research use:

ADMET, Drug-drug interactions, Drug metabolism, Drug transporter, Hepatotoxicity

Strain:

HsdSage:SD-Slc22a2^em1Sage

Produced in:

U.S. Cryopreserved

Research use:

Drug transporter, ADMET, Drug-drug interactions, Drug metabolism, Hepatotoxicity

Strain:

HsdSage:SD-Oprm1^em1Sage

Produced in:

U.S. Cryopreserved

Research use:

Addiction, Analgesia, Neuroscience, Nociception, Pain

Strain:

HsdSage:SD-Tp53^em1Sage

Produced in:

U.S. Cryopreserved

Research use:

Autoimmune disease, Cancer, Hematopoiesis, Infectious disease, Oncology, Vaccine development, Xenografts

Strain:

HsdSage:SD-Ngfr^em1Sage

Produced in:

U.S. Cryopreserved

Research use:

Neuroscience, Analgesia, Neuronal apoptosis, Nociception, Pain

Strain:

HsdSage:LE-Park2^em1Sage

Produced in:

U.S.

Research use:

Metabolism, Neuroscience, Parkinson's disease, Dopaminergic cell toxicity

Strain:

HsdSage:LE-Park7^em1Sage

Produced in:

U.S. Cryopreserved

Research use:

Neuroscience, Parkinson's disease, Dopaminergic cell toxicity

Strain:

HsdSage:LE-Pvalb^{em1(IRES-Cre)Sage}

Produced in:

U.S.

Research use:

Neuroscience, Cre Tool for conditional expression or deletion in PV+ neurons, Expression/knockout of floxed genes, Neuroscience, Optogenetics

Strain:

HsdSage:LE-Pink1^em1Sage

Produced in:

U.S.

Research use:

Neuroscience, Parkinson's disease, Stress-induced neurological dysfunction

Strain:

HsdSage:LE-Pink1^em1SagePark2^em1Sage

Produced in:

U.S.

Research use:

Neuroscience, Parkinson's disease, Stress-induced neurological dysfunction

Strain:

HsdSage:SD-Ppara^em1Sage

Produced in:

U.S. Cryopreserved

Research use:

ADMET, Autoimmune disorders, Cell proliferation, Drug metabolism, Diabetes, Immunology, Inflammation, Lipid metabolism, Obesity, Wound healing, Xenobiotic

Strain:

HsdSage:SD-Prkdc^em1Sage

Produced in:

U.S. Cryopreserved

Research use:

Immunology, Cancer metastasis, Oncology, Tumor cell growth, Xenograft

Strain:

HsdSage:SD-Pten^em1Sage

Produced in:

U.S. Cryopreserved

Research use:

Autism, Neuroscience, Cancer, Neuroscience, Oncology

Strain:

HsdSage:SD-Nr1i2^em1Sage

Produced in:

U.S. Cryopreserved

Research use:

ADMET, Cholestasis, Cytochrome p450 pathways, Drug metabolism, Hepatotoxicity, Xenobiotic

Strain:

HsdSage:SD-Nr1i2^em1SageNr1i3^em1Sage

Produced in:

U.S. Cryopreserved

Research use:

ADMET, Cholestasis, Cytochrome p450 pathways, Drug metabolism, Hepatotoxicity, Xenobiotic

Strain:

HsdSage:SD-NR1i2/NR1i3/AHR^em1Sage

Produced in:

U.S. Cryopreserved

Research use:

ADMET, Cholestasis, Cytochrome p450 pathways, Drug metabolism, Hepatotoxicity, Xenobiotic

Strain:

F344-Rag1^em1Sage/SageHsd

Produced in:

U.S. Cryopreserved

Research use:

Cancer metastasis, Immunology, Inflammation/Autoimmune disorders, Oncology, Thrombosis/Cardiac fibrosis, Vaccine development, Xenograft

Strain:

HsdSage:SD-Rag1^em1Sage

Produced in:

U.S. Cryopreserved

Research use:

Oncology, Cancer metastasis, Hematopoieses, Immunology, Inflammation/Autoimmune disorders, Infectious disease, Thrombosis/Cardiac fibrosis, Vaccine development, Vascular defects, Xenograft

Strain:

F344-Rag2^em1Sage/SageHsd

Produced in:

U.S. Cryopreserved

Research use:

Cancer metastasis, Inflammation/Autoimmune disorders, Thrombosis/Cardiac fibrosis, Vaccine development, Vascular defects, Xenograft

Strain:

HsdSage:SD-Rag2^em1sage

Produced in:

U.S.

Research use:

Infectious disease, Oncology, Vaccines, Cancer metastasis, Immunology, Inflammation/Autoimmune disorders, Hematopoieses, Thrombosis/Cardiac fibrosis, Vascular defects, Xenograft

Strain:

HsdSage:SD-Rbfox1^em1Sage

Produced in:

U.S. Cryopreserved

Research use:

Autism (ASD), Neurodegenerative Disorders, Neuroscience

Strain:

HsdSage: LE-SSt.Cre^em1Sage

Produced in:

U.S. Cryopreserved

Research use:

Cre Tool for conditional expression or deletion in SST+ neurons, Expression/knockout of floxed genes, Neuroscience, Optogenetics

Strain:

HsdSage:SD-Tbx21^em1Sage

Produced in:

U.S. Cryopreserved

Research use:

Asthma, Colitis, Crohn's disease, Immunology, Inflammation/Autoimmune disorders, Multiple sclerosis, Oncology, Platelet defects/Platelet aggregation, Renal dysplasia, Rheumatoid arthritis, Thrombosis/Cardiac fibrosis, Vascular defects

Strain:

HsdSage:LE-Rosa26^{em1(tdTomato)Sage}

Produced in:

U.S.

Research use:

Neuroscience, Tomato fluorescence, Expression of td, Optogenetics, Tomato fluorescence when Cre-recombinase is introduced

Strain:

HsdSage:LE-Tph2^{em1(T2A-Cre)Sage}

Produced in:

U.S. Cryopreserved

Research use:

Parkinson's disease, Cre Tool for conditional expression or deletion in Tph2+ neurons, Expression/knockout of floxed genes, Neuroscience, Optogenetics

Strain:

HsdSage:SD-Trpv1^em1Sage

Produced in:

U.S. Cryopreserved

Research use:

Neuroscience, Analgesia, Cannabinoids, Nociception, Pain, Thermoregulation

Strain:

HsdSage:SD-TH^{em1(IRES-Cre)Sage}

Produced in:

U.S.

Research use:

Neuroscience, Cre Tool for conditional expression or deletion in Th+ neurons, DREADD, Expression/knockout of floxed genes, Optogenetics

Strain:

HsdSage:LE-VGAT^{em1(IRES-Cre)Sage}

Produced in:

U.S. Cryopreserved

Research use:

Cre Tool for conditional expression or deletion in VGAT+ neurons, Expression/knockout of floxed genes, Neuroscience, Optogenetics

Strain:

HsdSage:LE-VIP^{em1(T2A-Cre)Sage}

Produced in:

U.S. Cryopreserved

Research use:

Neuroscience, Cre Tool for conditional expression or deletion in VIP+ neurons, Expression/knockout of floxed genes, Neuroscience, Optogenetics